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Title: | Ventricular metastasis resulting in disseminated intravascular coagulation. | Austin Authors: | John, Thomas ;Davis, Ian D | Affiliation: | tom.john@ludwig.edu.au. Ludwig Institute Oncology Unit, Austin Health, Heidelberg, Victoria 3084, Australia |
Issue Date: | 24-May-2005 | Publication information: | World Journal of Surgical Oncology 2005; 3(1): 29 | Abstract: | BACKGROUND: Disseminated Intravascular Coagulation (DIC) complicates up to 7% of malignancies, the commonest solid organ association being adenocarcinoma. Transitional Cell Carcinoma (TCC) has rarely been associated with DIC. CASE PRESENTATION: A 74-year-old woman with TCC bladder and DIC was found to have a cardiac lesion suspicious for metastatic disease. The DIC improved with infusion of plasma and administration of Vitamin K, however the cardiac lesion was deemed inoperable and chemotherapy inappropriate; given the patients functional status. We postulate that direct activation of the coagulation cascade by the intraventricular metastasis probably triggered the coagulopathy in this patient. CONCLUSION: Cardiac metastases should be considered in cancer patients with otherwise unexplained DIC. This may influence treatment choices. | Gov't Doc #: | 15913454 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/9930 | DOI: | 10.1186/1477-7819-3-29 | Journal: | World journal of surgical oncology | URL: | https://pubmed.ncbi.nlm.nih.gov/15913454 | Type: | Journal Article |
Appears in Collections: | Journal articles |
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