Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9891
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dc.contributor.authorIuliano-Burns, Sandraen
dc.contributor.authorStone, Jenniferen
dc.contributor.authorHopper, John Len
dc.contributor.authorSeeman, Egoen
dc.date.accessioned2015-05-15T23:10:03Z
dc.date.available2015-05-15T23:10:03Z
dc.date.issued2005-03-22en
dc.identifier.citationOsteoporosis International : A Journal Established As Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of The Usa 2005; 16(10): 1225-32en
dc.identifier.govdoc15782284en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/9891en
dc.description.abstractExercise and improved nutrition offer safe, low-cost and widely applicable approaches to potentially reduce the burden of fractures. We conducted a cross-sectional study of 30 monozygotic and 26 dizygotic male twin pairs, aged 7-20 years to test the following hypotheses: (1) Associations between bone mass and dimensions and exercise are greater than between bone mass and dimensions and protein or calcium intakes; (2) exercise or nutrient intake are associated with appendicular bone mass before puberty and axial bone mass during and after puberty. Total body and posteroanterior (PA) lumbar spine bone mineral content (BMC) and mid-femoral shaft dimensions were measured using dual energy X-ray absorptometry (DEXA). Relationships between within-pair differences in nutrient intake (determined by weighed-food diaries) or exercise duration (determined by questionnaire) and within-pair differences in BMC and bone dimensions were tested using linear regression analysis. In multivariate analyses, within-pair differences in exercise duration were associated with within-pair differences in total body, leg and spine BMC, and cortical thickness. Every-hour-per-week difference in exercise was associated with a 31-g (1.2%) difference in total body BMC, a 10-g (1.4%) difference in leg BMC, a 0.5-g difference in spine BMC and a 0.1-mm difference in cortical thickness ( p <0.01- p <0.1). A 1-g difference in protein intake was associated with a 0.8-g (0.4%) difference in arm BMC ( p <0.05). These relationships were present in peri-pubertal and post-pubertal pairs but not in pre-pubertal pairs. Exercise during growth appears to have greater skeletal benefits than variations in protein or calcium intakes, with the site-specific effects evident in more mature twins.en
dc.language.isoenen
dc.subject.otherAbsorptiometry, Photonen
dc.subject.otherAdolescenten
dc.subject.otherAdulten
dc.subject.otherAnthropometryen
dc.subject.otherBone Density.physiologyen
dc.subject.otherCalcium, Dietary.administration & dosageen
dc.subject.otherChilden
dc.subject.otherCross-Sectional Studiesen
dc.subject.otherDieten
dc.subject.otherDietary Proteins.administration & dosageen
dc.subject.otherExercise.physiologyen
dc.subject.otherGrowth.physiologyen
dc.subject.otherHumansen
dc.subject.otherMaleen
dc.subject.otherTwins.physiologyen
dc.titleDiet and exercise during growth have site-specific skeletal effects: a co-twin control study.en
dc.typeJournal Articleen
dc.identifier.journaltitleOsteoporosis Internationalen
dc.identifier.affiliationDepartment of Endocrinology, Austin Health, University of Melbourne, Studley Road, 3084 Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1007/s00198-004-1830-zen
dc.description.pages1225-32en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/15782284en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptMedicine (University of Melbourne)-
crisitem.author.deptEndocrinology-
crisitem.author.deptEndocrinology-
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