Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9754
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dc.contributor.authorBarnes, Mareeen
dc.contributor.authorMcEvoy, R Douglasen
dc.contributor.authorBanks, Siobhanen
dc.contributor.authorTarquinio, Natalieen
dc.contributor.authorMurray, Christopher Gen
dc.contributor.authorVowles, Normanen
dc.contributor.authorPierce, Robert Jen
dc.date.accessioned2015-05-15T22:57:47Z
dc.date.available2015-05-15T22:57:47Z
dc.date.issued2004-06-16en
dc.identifier.citationAmerican Journal of Respiratory and Critical Care Medicine 2004; 170(6): 656-64en
dc.identifier.govdoc15201136en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/9754en
dc.description.abstractThe efficacy of currently recommended treatments is uncertain in patients with mild to moderate obstructive sleep apnea (apnea-hypopnea index [AHI], 5-30). A group of 114 sleep clinic patients with an AHI of 5-30 have participated in a randomized controlled crossover trial of 3 months of treatment with each of nasal continuous positive airway pressure (CPAP), a mandibular advancement splint, and a placebo tablet. Outcomes were sleep fragmentation and hypoxemia, daytime sleepiness, quality of life, neurobehavioral function, and blood pressure. Both active treatments improved sleep outcomes, but positive airway pressure had a greater effect. The quality of life, symptoms, and subjective but not objective sleepiness improved to a similar degree with both treatments; however, many of the improvements seen in neuropsychologic function and mood were not better than the placebo effect. Some aspects of nocturnal blood pressure were improved with the splint but not with CPAP. This study has shown that although both CPAP and mandibular advancement splint effectively treated sleep-disordered breathing and sleepiness, the expected response in neurobehavioral function was incomplete. This may be due to the splint having a lesser therapeutic effect and CPAP being poorly tolerated and therefore used less in this patient group.en
dc.language.isoenen
dc.subject.otherContinuous Positive Airway Pressure.methodsen
dc.subject.otherCross-Over Studiesen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherMaleen
dc.subject.otherMandibular Advancement.instrumentationen
dc.subject.otherMiddle Ageden
dc.subject.otherOrthodontic Appliances, Removableen
dc.subject.otherQuality of Lifeen
dc.subject.otherSleep Apnea, Obstructive.therapyen
dc.subject.otherTreatment Outcomeen
dc.titleEfficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea.en
dc.typeJournal Articleen
dc.identifier.journaltitleAmerican Journal of Respiratory and Critical Care Medicineen
dc.identifier.affiliationInstitute for Breathing and Sleep, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1164/rccm.200311-1571OCen
dc.description.pages656-64en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/15201136en
dc.type.austinJournal Articleen
local.name.researcherBarnes, Maree
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptInstitute for Breathing and Sleep-
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