Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9707
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dc.contributor.authorMartin, Gen
dc.contributor.authorSewell, Richard Ben
dc.contributor.authorYeomans, Neville Den
dc.contributor.authorSmallwood, R Aen
dc.date.accessioned2015-05-15T22:54:00Z
dc.date.available2015-05-15T22:54:00Z
dc.date.issued1992-07-01en
dc.identifier.citationClinical and Experimental Pharmacology & Physiology; 19(7): 537-9en
dc.identifier.govdoc1499150en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/9707en
dc.description.abstract1. The hepatic reticulo-endothelial cell population is generally assumed to increase in size, along with the liver, during ageing in rats. However, this has not been rigorously established. 2. Using electron microscopy and stereological techniques, the present study has shown that the volume densities of hepatocytes and Kupffer cells (and probably also of endothelial cells, fat storing cells and the extracellular space) of the livers of female Sprague-Dawley rats are the same at 2 and 24-25 months of age. 3. This result indicates that the increase in size of the liver during ageing in the rat is associated with an equivalent increase in the volume of each cell population and the extracellular space.en
dc.language.isoenen
dc.subject.otherAging.physiologyen
dc.subject.otherAnimalsen
dc.subject.otherExtracellular Space.physiologyen
dc.subject.otherFemaleen
dc.subject.otherKupffer Cells.cytologyen
dc.subject.otherLiver.cytologyen
dc.subject.otherRatsen
dc.subject.otherRats, Inbred Strainsen
dc.titleAgeing has no effect on the volume density of hepatocytes, reticulo-endothelial cells or the extracellular space in livers of female Sprague-Dawley rats.en
dc.typeJournal Articleen
dc.identifier.journaltitleClinical and Experimental Pharmacology & Physiologyen
dc.identifier.affiliationDepartment of Medicine, Heidelberg Repatriation Hospital, Melbourne, Victoria, Australiaen
dc.description.pages537-9en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/1499150en
dc.type.austinJournal Articleen
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptMedicine (University of Melbourne)-
crisitem.author.deptOffice for Research-
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