Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9671
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dc.contributor.authorShah, Pallav J-
dc.contributor.authorHare, David L-
dc.contributor.authorRaman, Jai S-
dc.contributor.authorGordon, Ian R-
dc.contributor.authorChan, Robert K-
dc.contributor.authorHorowitz, John D-
dc.contributor.authorRosalion, Alexander-
dc.contributor.authorBuxton, Brian F-
dc.date.accessioned2015-05-15T22:51:08Z
dc.date.available2015-05-15T22:51:08Z
dc.date.issued2003-11-01-
dc.identifier.citationThe Journal of Thoracic and Cardiovascular Surgery; 126(5): 1320-7en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/9671en
dc.description.abstractThe aim was to prospectively analyze all-cause mortality, predictors of survival, and late functional results after myocardial revascularization for ischemic cardiomyopathy over a 10-year follow-up.We prospectively studied 57 patients with stable coronary artery disease and poor left ventricular ejection function (<35%), enrolled between 1989 and 1994. Stress thallium was analyzed in 37 patients to identify reversible ischemia. To avoid patients with a stunned myocardium, we excluded those with unstable angina or myocardial infarction within the previous 4 weeks. Mean age of the patients was 67 +/- 8 years, and 93% of patients were men. Mean left ventricular ejection fraction was 0.28 +/- 0.04, 50% were in Canadian Cardiovascular Society angina class III-IV, and 65% were in New York Heart Association functional class III-IV.Operative mortality was 1.7% (1/57). The mean left ventricular ejection fraction (0.30) at 15 months postoperatively did not change from before operation (0.28, P =.09). There were 8 deaths at 1 year and 42 deaths over the course of the study, producing a survival of 82.5% at 1 year, 55.7% at 5 years, and 23.9% at 10 years (95% confidence interval: 14.6%-39.1%). Symptom-free survival was 77.2% at 1 year and 20.3% at 10 years. The leading cause of death was heart failure in 29% (12/42). Multivariate analysis showed that large reversible defects on stress thallium were associated with improved left ventricular ejection fraction at 1 year (P =.01) but only male sex was associated with improved long-term survival (P =.036).Myocardial revascularization for ischemic cardiomyopathy is associated with good functional relief from the symptoms of angina initially and, to a lesser extent, heart failure. Revascularization may have the advantage of preserving the remaining left ventricular function. However, the long-term mortality remains high.en
dc.language.isoenen
dc.subject.otherAgeden
dc.subject.otherAnalysis of Varianceen
dc.subject.otherCardiomyopathy, Dilated.diagnosis.mortality.surgeryen
dc.subject.otherCoronary Artery Bypass.methods.mortalityen
dc.subject.otherFemaleen
dc.subject.otherFollow-Up Studiesen
dc.subject.otherHumansen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherMyocardial Ischemia.diagnosis.mortality.surgeryen
dc.subject.otherMyocardial Revascularization.methods.mortalityen
dc.subject.otherPredictive Value of Testsen
dc.subject.otherProbabilityen
dc.subject.otherProportional Hazards Modelsen
dc.subject.otherProspective Studiesen
dc.subject.otherRisk Assessmenten
dc.subject.otherSampling Studiesen
dc.subject.otherSeverity of Illness Indexen
dc.subject.otherSurvival Analysisen
dc.subject.otherTime Factorsen
dc.subject.otherTreatment Outcomeen
dc.subject.otherVentricular Dysfunction, Left.diagnosisen
dc.titleSurvival after myocardial revascularization for ischemic cardiomyopathy: a prospective ten-year follow-up study.en
dc.typeJournal Articleen
dc.identifier.journaltitleThe Journal of thoracic and cardiovascular surgeryen
dc.identifier.affiliationDepartment of Cardiac Surgery, Austin Hospital, Melbourne, Victoria, Australiaen
dc.identifier.doi10.1016/s0022-5223(03)00809-2en
dc.description.pages1320-7en
dc.type.contentTexten
dc.identifier.orcid0000-0001-9554-6556en
dc.identifier.pubmedid14666002-
dc.type.austinJournal Articleen
local.name.researcherBuxton, Brian F
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptCardiology-
crisitem.author.deptCardiac Surgery-
crisitem.author.deptCardiology-
crisitem.author.deptCardiac Surgery-
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