Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9559
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dc.contributor.authorJohnston, Colin Ien
dc.contributor.authorBurrell, Louise Men
dc.contributor.authorPerich, Ren
dc.contributor.authorJandeleit, Ken
dc.contributor.authorJackson, Ben
dc.date.accessioned2015-05-15T22:42:15Z
dc.date.available2015-05-15T22:42:15Z
dc.date.issued1992-05-16en
dc.identifier.citationClinical and Experimental Pharmacology & Physiology. Supplement; 19(): 1-5en
dc.identifier.govdoc1327595en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/9559en
dc.description.abstract1. The components of the renin-angiotensin system exist in many cardiovascular tissues (heart vessels, kidneys, adrenal glands). 2. Angiotensin-converting enzyme (ACE) is similar in somatic cells from all these sites. 3. ACE contains two catalytic sites that have different conformation requirements. This suggests that each site may have different substrates and that specific inhibitors could be developed for each site. 4. The cardiovascular functions of tissue ACE may include the regulation of regional blood flow, modulation of local sympathetic activity, stimulation of hyperplasia and hypertrophy and the mediation of inflammation.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherHumansen
dc.subject.otherHypertrophy.metabolismen
dc.subject.otherPeptidyl-Dipeptidase A.metabolismen
dc.subject.otherRenin-Angiotensin System.physiologyen
dc.titleThe tissue renin-angiotensin system and its functional role.en
dc.typeJournal Articleen
dc.identifier.journaltitleClinical and Experimental Pharmacology & Physiology. Supplementen
dc.identifier.affiliationUniversity of Melbourne Department of Medicine, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages1-5en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/1327595en
dc.type.austinJournal Articleen
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.cerifentitytypePublications-
crisitem.author.deptCardiology-
crisitem.author.deptGeneral Medicine-
crisitem.author.deptMedicine (University of Melbourne)-
crisitem.author.deptGastroenterology and Hepatology-
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