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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9559
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DC FieldValueLanguage
dc.contributor.authorJohnston, Colin I-
dc.contributor.authorBurrell, Louise M-
dc.contributor.authorPerich, R-
dc.contributor.authorJandeleit, K-
dc.contributor.authorJackson, B-
dc.date.accessioned2015-05-15T22:42:15Z
dc.date.available2015-05-15T22:42:15Z
dc.date.issued1992-05-16-
dc.identifier.citationClinical and Experimental Pharmacology & Physiology. Supplement; 19(): 1-5en_US
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/9559en
dc.description.abstract1. The components of the renin-angiotensin system exist in many cardiovascular tissues (heart vessels, kidneys, adrenal glands). 2. Angiotensin-converting enzyme (ACE) is similar in somatic cells from all these sites. 3. ACE contains two catalytic sites that have different conformation requirements. This suggests that each site may have different substrates and that specific inhibitors could be developed for each site. 4. The cardiovascular functions of tissue ACE may include the regulation of regional blood flow, modulation of local sympathetic activity, stimulation of hyperplasia and hypertrophy and the mediation of inflammation.en_US
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherHumansen
dc.subject.otherHypertrophy.metabolismen
dc.subject.otherPeptidyl-Dipeptidase A.metabolismen
dc.subject.otherRenin-Angiotensin System.physiologyen
dc.titleThe tissue renin-angiotensin system and its functional role.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleClinical and Experimental Pharmacology & Physiology. Supplementen_US
dc.identifier.affiliationMedicine (University of Melbourne)en_US
dc.description.pages1-5en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/1327595en
dc.type.contentTexten_US
dc.type.austinJournal Articleen
local.name.researcherBurrell, Louise M
item.grantfulltextnone-
item.openairetypeJournal Article-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.deptCardiology-
crisitem.author.deptGeneral Medicine-
crisitem.author.deptMedicine (University of Melbourne)-
crisitem.author.deptGastroenterology and Hepatology-
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