Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9417
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dc.contributor.authorStork, Jacinda Len
dc.contributor.authorLevi, Christopher Ren
dc.contributor.authorChambers, Brian Ren
dc.contributor.authorAbbott, Anne Len
dc.contributor.authorDonnan, Geoffrey Aen
dc.date.accessioned2015-05-15T22:30:22Z
dc.date.available2015-05-15T22:30:22Z
dc.date.issued2002-08-01en
dc.identifier.citationStroke; A Journal of Cerebral Circulation; 33(8): 2082-5en
dc.identifier.govdoc12154267en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/9417en
dc.description.abstractHigh numbers of microembolic signals (MES) have been associated with increased risk of postoperative stroke after carotid endarterectomy (CEA). We sought to identify factors predictive of postoperative MES.Transcranial Doppler monitoring of the ipsilateral middle cerebral artery for MES was performed for 30 minutes during the first postoperative hour in sequential patients undergoing CEA. Stepwise binomial logistic regression analysis was performed to identify preoperative and intraoperative variables that predicted the occurrence of postoperative MES.We studied 141 patients (mean age, 69 years); 102 (72%) were male, and 69 (49%) had at least 1 MES (range, 1 to 118) detected in the first postoperative hour. The risk of postoperative MES was greater in women (P=0.027), patients not receiving antiplatelet therapy (P=0.033), and patients undergoing left-sided CEA (P=0.049). Other variables such as residual stenosis seen on completion angiography and operative technique were not associated with postoperative MES.Postoperative MES were most likely in women, patients not receiving preoperative antiplatelet therapy, and patients who had a left CEA. Microembolism might explain why these same factors are associated with higher rates of perioperative stroke.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherAgeden
dc.subject.otherAged, 80 and overen
dc.subject.otherDextrans.therapeutic useen
dc.subject.otherEndarterectomy, Carotid.adverse effectsen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherIntracranial Embolism.etiology.prevention & control.ultrasonographyen
dc.subject.otherIntraoperative Perioden
dc.subject.otherLogistic Modelsen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherMiddle Cerebral Artery.ultrasonographyen
dc.subject.otherMonitoring, Physiologicen
dc.subject.otherMultivariate Analysisen
dc.subject.otherPlatelet Aggregation Inhibitors.therapeutic useen
dc.subject.otherPostoperative Perioden
dc.subject.otherRandomized Controlled Trials as Topic.statistics & numerical dataen
dc.subject.otherRetrospective Studiesen
dc.subject.otherRisk Factorsen
dc.subject.otherSex Factorsen
dc.subject.otherStroke.etiology.prevention & controlen
dc.subject.otherUltrasonography, Doppler, Transcranialen
dc.titlePossible determinants of early microembolism after carotid endarterectomy.en
dc.typeJournal Articleen
dc.identifier.journaltitleStrokeen
dc.identifier.affiliationNational Stroke Research Institute, Austin and Repatriation Medical Centre, West Heidelberg, Victoria 3081, Australiaen
dc.description.pages2082-5en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/12154267en
dc.type.austinJournal Articleen
local.name.researcherChambers, Brian R
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptNeurology-
crisitem.author.deptThe Florey Institute of Neuroscience and Mental Health-
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