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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/35339
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dc.contributor.authorChow, Eric P F-
dc.contributor.authorStevens, Kerrie-
dc.contributor.authorDe Petra, Vesna-
dc.contributor.authorChen, Marcus Y-
dc.contributor.authorBradshaw, Catriona S-
dc.contributor.authorSherry, Norelle L-
dc.contributor.authorBarbee, Lindley A-
dc.contributor.authorVodstrcil, Lenka A-
dc.contributor.authorAguirre, Ivette-
dc.contributor.authorSeib, Kate L-
dc.contributor.authorMaddaford, Kate-
dc.contributor.authorWilliamson, Deborah A-
dc.contributor.authorHowden, Benjamin P-
dc.contributor.authorFairley, Christopher K-
dc.date2024-
dc.date.accessioned2024-06-21T06:27:07Z-
dc.date.available2024-06-21T06:27:07Z-
dc.date.issued2024-11-15-
dc.identifier.citationThe Journal of Infectious Diseases 2024-11-15; 230(5)en_US
dc.identifier.issn1537-6613-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/35339-
dc.description.abstractWhile ceftriaxone remains the first-line treatment for gonorrhoea, the US CDC recommended cefixime as a second-line treatment in 2021. We tested 1176 Neisseria gonorrhoeae isolates among clients attending the Melbourne Sexual Health Centre in 2021-2022. The prevalence of cefixime resistance was 6.3% (74/1176), azithromycin resistance was 4.9% (58/1176) and ceftriaxone resistance was 0% (0/1176). Cefixime resistance was the highest among women (16.4%, 10/61), followed by men-who-have-sex-with-women (6.4%, 7/109), and men-who-have-sex-with-men (5.8%, 57/982). The prevalence of cefixime-resistant N. gonorrhoeae exceeds the threshold of the 5% resistance level recommended by the World Health Organization; and thus, cefixime treatment would have limited benefits in Australia.en_US
dc.language.isoeng-
dc.subjectGonorrhoeaen_US
dc.subjectNeisseria gonorrhoeaeen_US
dc.subjectantimicrobial resistanceen_US
dc.subjectresistanceen_US
dc.subjecttreatmenten_US
dc.titlePrevalence of cefixime-resistant Neisseria gonorrhoeae in Melbourne, Australia, 2021-2022.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleThe Journal of Infectious Diseasesen_US
dc.identifier.affiliationMelbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.;School of Translational Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.;Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.en_US
dc.identifier.affiliationMicrobiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.en_US
dc.identifier.affiliationMelbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.;Microbiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.en_US
dc.identifier.affiliationInfectious Diseasesen_US
dc.identifier.affiliationMicrobiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.;Department of Infectious Diseases & Immunology, Austin Health, Heidelberg, Victoria, Australia.en_US
dc.identifier.affiliationDepartment of Medicine, University of Washington, Seattle, Washington, USA.;Public Health - Seattle & King County, HIV/STD Program, Seattle, Washington, USA.en_US
dc.identifier.affiliationMelbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.;School of Translational Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.;Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.en_US
dc.identifier.affiliationInstitute for Glycomics, Griffith University, Southport, Queensland, Australia.en_US
dc.identifier.affiliationMelbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.;School of Translational Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.en_US
dc.identifier.affiliationVictorian Infectious Disease Reference Laboratory, The Royal Melbourne Hospital, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.;Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.;Walter and Eliza Hall Institute, Melbourne, Victoria, Australia.en_US
dc.identifier.affiliationMicrobiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.;Department of Infectious Diseases & Immunology, Austin Health, Heidelberg, Victoria, Australia.;Centre for Pathogen Genomics, University of Melbourne, Melbourne, Victoria, Australia.en_US
dc.identifier.affiliationMelbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.;School of Translational Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.en_US
dc.identifier.doi10.1093/infdis/jiae313en_US
dc.type.contentTexten_US
dc.identifier.orcid0000-0003-1766-0657en_US
dc.identifier.orcid0000-0002-6643-5678en_US
dc.identifier.pubmedid38877763-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptMicrobiology-
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