Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/34439
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Rahimi, Matthew M | - |
dc.contributor.author | Vakulin, Andrew | - |
dc.contributor.author | McEvoy, R Doug | - |
dc.contributor.author | Barnes, Maree | - |
dc.contributor.author | Quinn, Stephen J | - |
dc.contributor.author | Mercer, Jeremy D | - |
dc.contributor.author | O'Grady, Amanda | - |
dc.contributor.author | Antic, Nick A | - |
dc.contributor.author | Catcheside, Peter G | - |
dc.date | 2023 | - |
dc.date.accessioned | 2023-12-13T05:24:54Z | - |
dc.date.available | 2023-12-13T05:24:54Z | - |
dc.date.issued | 2024-02 | - |
dc.identifier.citation | Annals of the American Thoracic Society 2024-02; 21(2) | en_US |
dc.identifier.issn | 2325-6621 | - |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/34439 | - |
dc.description.abstract | Around 20-35% of obstructive sleep apnoea (OSA) patients show supine-isolated OSA, where supine sleep avoidance could be an effective therapy. However, traditional supine discomfort-based methods show poor tolerance and compliance to treatment, so cannot be recommended. Supine-alarm devices show promise, but evidence to support favourable adherence to treatment and effectiveness at reducing excessive daytime sleepiness compared to continuous positive airway pressure (CPAP) remains limited. To establish if alarm-based supine-avoidance treatment in supine-isolated OSA patients is non-inferior to CPAP in reducing daytime sleepiness. Following baseline questionnaires and in-home supine-time and polysomnography assessments, patients with supine-isolated OSA and Epworth sleepiness scale (ESS) score ≥8 were randomised to ≥6 weeks of supine-avoidance or CPAP treatment, followed by cross-over to the remaining treatment with repeat assessments. Non-inferiority was assessed from change in ESS with supine-avoidance compared to CPAP using a pre-specified non-inferiority margin of 1.5. Average nightly treatment use over all nights, and treatment efficacy and effectiveness at reducing respiratory disturbances were also compared between treatments. The reduction in sleepiness score with supine-avoidance (mean [95%CI] -1.9 [-2.8 to -1.0]) was non-inferior to CPAP (-2.4 [-3.3 to -1.4], supine-avoidance-CPAP difference -0.4 [-1.3 to 0.6]) and the lower confidence limit did not cross the non-inferiority margin of 1.5, p=0.021. Average treatment usage was higher with supine-avoidance compared to CPAP (mean ± SD 5.7 ± 2.4 versus 3.9 ± 2.7 h/night, p<0.001). In patients with supine-isolated OSA, vibro-tactile supine alarm device therapy is non-inferior to CPAP for reducing sleepiness and shows superior treatment adherence. | en_US |
dc.language.iso | eng | - |
dc.title | Comparative Effectiveness of Supine-Avoidance versus Continuous Positive Airway Pressure for Treating Supine-isolated Sleep Apnea. | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journaltitle | Annals of the American Thoracic Society | en_US |
dc.identifier.affiliation | Flinders University Faculty of Medicine Nursing and Health Sciences, 64767, Adelaide, Australia. | en_US |
dc.identifier.affiliation | Adelaide Institute of Sleep Health, Adelaide, South Australia, Australia.;Repatriation General Hospital, Sleep and Respiratory Medicine, Adelaide, South Australia, Australia. | en_US |
dc.identifier.affiliation | Flinders University, Adelaide, Australia. | en_US |
dc.identifier.affiliation | Institute for Breathing and Sleep | en_US |
dc.identifier.affiliation | Swinburne University of Technology, 3783, 7. Department of Statistics, Data Science and Epidemiology, Hawthorn, Victoria, Australia. | en_US |
dc.identifier.affiliation | Southern Adelaide Local Health Network, 6677, Bedford Park, South Australia, Australia. | en_US |
dc.identifier.affiliation | Adelaide Institute of Sleep Health, Adelaide, South Australia, Australia. | en_US |
dc.identifier.affiliation | The Adelaide Institute of Sleep Health, The Repatriation General Hospital, Daw Park, South Australia, Australia.;Flinders University, Adelaide, Australia. | en_US |
dc.identifier.affiliation | Flinders University , College of Medicine and Public Health, Bedford Park, South Australia, Australia. | en_US |
dc.identifier.doi | 10.1513/AnnalsATS.202309-753OC | en_US |
dc.type.content | Text | en_US |
dc.identifier.orcid | 0000-0002-7799-9348 | en_US |
dc.identifier.pubmedid | 38015501 | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
crisitem.author.dept | Institute for Breathing and Sleep | - |
Appears in Collections: | Journal articles |
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.