Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/34376
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dc.contributor.authorAbdelkarim, Hussam-
dc.contributor.authorCiampoli, Natasha-
dc.contributor.authorZwakman-Hessels, Lara-
dc.contributor.authorDarvall, Jai N-
dc.contributor.authorBellomo, Rinaldo-
dc.date2023-
dc.date.accessioned2023-12-13T05:24:34Z-
dc.date.available2023-12-13T05:24:34Z-
dc.date.issued2020-12-
dc.identifier.citationCritical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine 2020-12; 22(4)en_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/34376-
dc.description.abstractObjective: To test the effectiveness of chewing gum in the prophylaxis of postoperative nausea and vomiting (PONV) in patients admitted to the intensive care unit (ICU) after surgery. Design: Prospective, open label, pilot randomised controlled trial. Setting: Two metropolitan ICUs. Participants: Ninety postoperative adult patients admitted to the ICU. Intervention: Patients administered chewing gum, who chewed for at least 15 minutes every 4 hours, were compared with a control group, who were administered a 20 mL sip of water orally every 4 hours. Main outcome measures: The primary outcome was the number of patient-reported episodes of nausea in the first 24 hours after the operation. Secondary outcomes included vomiting or dry retching episodes, and duration and severity of nausea. Results: Forty-six patients were randomly allocated to chewing gum and 44 patients to water. There was no difference between groups in the number of patients with nausea (10 [22%] chewing gum v 12 [27%] control patients; P = 0.72), nausea episodes (22 episodes; [median, 0; IQR, 0-0] v 21 episodes [median, 0; IQR, 0-1] per patient in each group respectively), vomiting/retching (2 [4%] chewing gum v 6 [14%] control patients; P = 0.24), or duration/severity of nausea. Conclusion: Regular postoperative administration of chewing gum in a surgical ICU patient cohort did not reduce nausea, vomiting or retching. The prevalence of PONV is less than previously reported. Our findings can inform future studies of PONV prophylaxis in post-surgical ICU patients. Trial registration: Australian New Zealand Clinical Trial Registry No. ACTRN12617001185358.en_US
dc.language.isoeng-
dc.titleChewing gum prophylaxis for postoperative nausea and vomiting in the intensive care unit: a pilot randomised controlled trial.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleCritical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicineen_US
dc.identifier.affiliationDepartment of Intensive care, Ballarat Health Service, Ballarat, VIC, Australia.en_US
dc.identifier.affiliationDepartment of Intensive Care, Epworth Eastern, Melbourne, VIC, Australia.en_US
dc.identifier.affiliationDepartment of Critical Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlandsen_US
dc.identifier.affiliationDepartment of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia.;Centre for Integrated Critical Care, School of Medicine, University of Melbourne, Melbourne, VIC, Australia.en_US
dc.identifier.affiliationCentre for Integrated Critical Care, School of Medicine, University of Melbourne, Melbourne, VIC, Australia.;Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia.en_US
dc.identifier.affiliationIntensive Careen_US
dc.identifier.doi10.51893/2020.4.OA4en_US
dc.type.contentTexten_US
dc.identifier.pubmedid38046876-
dc.description.volume22-
dc.description.issue4-
dc.description.startpage321-
dc.description.endpage326-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptIntensive Care-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
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