Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/34245
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dc.contributor.authorBuchholz, Vered-
dc.contributor.authorHazard, Riley-
dc.contributor.authorYin, Zoe-
dc.contributor.authorTran, Nghiep-
dc.contributor.authorYip, Sui Wah Sean-
dc.contributor.authorLe, Peter-
dc.contributor.authorKioussis, Benjamin-
dc.contributor.authorHinton, Jake-
dc.contributor.authorLiu, David Shi Hao-
dc.contributor.authorLee, Dong-Kyu-
dc.contributor.authorWeinberg, Laurence-
dc.date2023-
dc.date.accessioned2023-11-15T05:28:14Z-
dc.date.available2023-11-15T05:28:14Z-
dc.date.issued2023-11-06-
dc.identifier.citationBMC Research Notes 2023-11-06; 16(1)en_US
dc.identifier.issn1756-0500-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/34245-
dc.description.abstractTransthoracic esophagectomy is associated with significant morbidity and mortality. Therefore, it is imperative to optimize perioperative management and minimize complications. In this retrospective analysis, we evaluated the association between fluid balance and esophagectomy complications at a tertiary hospital in Melbourne, Australia, with a particular focus on respiratory morbidity and anastomotic leaks. Cumulative fluid balance was calculated intraoperatively, postoperatively in recovery postoperative day (POD) 0, and on POD 1 and 2. High and low fluid balance was defined as greater than or less than the median fluid balance, respectively, and postoperative surgical complications were graded using the Clavien-Dindo classification. In total, 109 patients, with an average age of 64 years, were included in this study. High fluid balance on POD 0, POD1 and POD 2 was associated with a higher incidence of anastomotic leak (OR 8.59; 95%CI: 2.64-39.0). High fluid balance on POD 2 was associated with more severe complications (of any type) (OR 3.33; 95%CI: 1.4-8.26) and severe pulmonary complications (OR 3.04; 95%CI: 1.27-7.67). For every 1 L extra cumulative fluid balance in POD 1, the odds of a major complication increase by 15%, while controlling for body mass index (BMI) and American Society of Anaesthesiologists (ASA) class. The results show that higher cumulative fluid balance is associated with worsening postoperative outcomes in patients undergoing transthoracic esophagectomy. Restricted fluid balance, especially postoperatively, may mitigate the risk of postoperative complications - however prospective trials are required to establish this definitively.en_US
dc.language.isoeng-
dc.subjectAnaesthesiaen_US
dc.subjectCanceren_US
dc.subjectEsophagectomyen_US
dc.subjectFluiden_US
dc.subjectFluid balanceen_US
dc.subjectSurgeryen_US
dc.titleThe impact of intraoperative and postoperative fluid balance on complications for transthoracic esophagectomy: a retrospective analysis.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleBMC Research Notesen_US
dc.identifier.affiliationSurgery (University of Melbourne)en_US
dc.identifier.affiliationAnaesthesiaen_US
dc.identifier.affiliationSurgeryen_US
dc.identifier.affiliationGeneral and Gastrointestinal Surgery Research Group, The University of Melbourne, Austin Precinct, Melbourne, Australia.en_US
dc.identifier.affiliationDepartment of Anesthesiology and Pain Medicine, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.en_US
dc.identifier.affiliationDepartment of Critical Care, University of Melbourne, Melbourne, Australia.en_US
dc.identifier.doi10.1186/s13104-023-06574-xen_US
dc.type.contentTexten_US
dc.identifier.pubmedid37932807-
dc.description.volume16-
dc.description.issue1-
dc.description.startpage315-
dc.subject.meshtermssecondaryEsophagectomy/adverse effects-
dc.subject.meshtermssecondaryEsophagectomy/methods-
dc.subject.meshtermssecondaryEsophageal Neoplasms/complications-
dc.subject.meshtermssecondaryEsophageal Neoplasms/surgery-
dc.subject.meshtermssecondaryAnastomotic Leak/surgery-
dc.subject.meshtermssecondaryPostoperative Complications/etiology-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairetypeJournal Article-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.deptSurgery-
crisitem.author.deptAnaesthesia-
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