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https://ahro.austin.org.au/austinjspui/handle/1/33443
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DC Field | Value | Language |
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dc.contributor.author | Gin, Julian | - |
dc.contributor.author | Yeoh, Julian | - |
dc.contributor.author | Hamilton, Garry W | - |
dc.contributor.author | Ajani, Andrew | - |
dc.contributor.author | Dinh, Diem | - |
dc.contributor.author | Brennan, Angela | - |
dc.contributor.author | Reid, Christopher M | - |
dc.contributor.author | Freeman, Melanie | - |
dc.contributor.author | Oqueli, Ernesto | - |
dc.contributor.author | Hiew, Chin | - |
dc.contributor.author | Stub, Dion | - |
dc.contributor.author | Chan, William | - |
dc.contributor.author | Picardo, Sandra | - |
dc.contributor.author | Yudi, Matias B | - |
dc.contributor.author | Horrigan, Mark | - |
dc.contributor.author | Farouque, Omar | - |
dc.contributor.author | Clark, David J | - |
dc.date | 2023 | - |
dc.date.accessioned | 2023-08-03T00:23:18Z | - |
dc.date.available | 2023-08-03T00:23:18Z | - |
dc.date.issued | 2024-01 | - |
dc.identifier.citation | Cardiovascular Revascularization Medicine: Including Molecular Interventions 2024-01; 58 | en_US |
dc.identifier.issn | 1878-0938 | - |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/33443 | - |
dc.description.abstract | Current evidence suggests that percutaneous coronary intervention for unprotected left main coronary artery disease (LMPCI) in selected patients is a safe alternative to coronary artery bypass grafting. However, real-world long-term survival data is limited. We analyzed 24,644 patients from the MIG (Melbourne Interventional Group) registry between 2005 and 2020. We compared baseline clinical and procedural characteristics, in-hospital and 30-day outcomes, and long-term survival between unprotected LMPCI and non-LMPCI among patients without ST-segment elevation myocardial infarction, cardiogenic shock, or cardiac arrest. Unprotected LMPCI patients (n = 185) were significantly older (mean age 72.0 vs. 64.6 years, p < 0.001), had higher prevalence of impaired ejection fraction (EF <50 %; 27.3 % vs. 14.9 %, p < 0.001) and lower estimated glomerular filtration rate < 60 ml/min/1.73m2 (40.9 % vs. 21.5 %, p < 0.001), and had greater use of intravascular ultrasound (21 % vs. 1 %, p < 0.001) and drug-eluting stents (p < 0.001). LMPCI was associated with longer hospital stay (4 days vs. 2 days, p < 0.001). There was no significant difference in other in-hospital outcomes, 30-day mortality (0.6 % vs. 0.6 %, p = 0.90), and major adverse cardiac events (1.7 % vs. 3 %, p = 0.28). Although the unadjusted Kaplan-Meier survival to 8 years was significantly less with LMPCI compared to non-LMPCI (p < 0.01), LMPCI was not a predictor of long-term survival up to 8 years after Cox regression analysis (HR 0.67, 95 % CI 0.40-1.13, p = 0.13). In this study, non-emergent unprotected LMPCI was uncommonly performed, and IVUS was underutilized. Despite greater co-morbidities, LMPCI patients had comparable 30-day outcomes to non-LMPCI, and LMPCI was not an independent predictor of long-term mortality. | en_US |
dc.language.iso | eng | - |
dc.subject | Left main coronary artery | en_US |
dc.subject | Mortality | en_US |
dc.subject | Percutaneous coronary intervention | en_US |
dc.title | Real-world long-term survival after non-emergent percutaneous coronary intervention to unprotected left main coronary artery - From the Melbourne Interventional Group (MIG) registry. | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journaltitle | Cardiovascular Revascularization Medicine: Including Molecular Interventions | en_US |
dc.identifier.affiliation | Cardiology | en_US |
dc.identifier.affiliation | Department of Cardiology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia. | en_US |
dc.identifier.affiliation | School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. | en_US |
dc.identifier.affiliation | School of Population Health, Curtin University, Perth, Western Australia, Australia. | en_US |
dc.identifier.affiliation | Department of Cardiology, Eastern Health, Melbourne, Victoria, Australia. | en_US |
dc.identifier.affiliation | Department of Cardiology, Grampians Health Ballarat, Ballarat, Victoria, Australia. | en_US |
dc.identifier.affiliation | Department of Cardiology, Barwon Health, Geelong, Victoria, Australia. | en_US |
dc.identifier.affiliation | School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Department of Cardiology, Alfred Health, Melbourne, Victoria, Australia. | en_US |
dc.identifier.affiliation | Department of Cardiology, Alfred Health, Melbourne, Victoria, Australia; Department of Cardiology, Western Health, Melbourne, Victoria, Australia. | en_US |
dc.identifier.doi | 10.1016/j.carrev.2023.07.005 | en_US |
dc.type.content | Text | en_US |
dc.identifier.pubmedid | 37500394 | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | University of Melbourne Clinical School | - |
Appears in Collections: | Journal articles |
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