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DC Field | Value | Language |
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dc.contributor.author | Mazzinari, Guido | - |
dc.contributor.author | Zampieri, Fernando G | - |
dc.contributor.author | Ball, Lorenzo | - |
dc.contributor.author | Campos, Niklas S | - |
dc.contributor.author | Bluth, Thomas | - |
dc.contributor.author | Hemmes, Sabrine N T | - |
dc.contributor.author | Ferrando, Carlos | - |
dc.contributor.author | Librero, Julian | - |
dc.contributor.author | Soro, Marina | - |
dc.contributor.author | Pelosi, Paolo | - |
dc.contributor.author | Gama de Abreu, Marcelo | - |
dc.contributor.author | Schultz, Marcus J | - |
dc.contributor.author | Serpa Neto, Ary | - |
dc.date | 2022 | - |
dc.date.accessioned | 2023-06-07T02:47:25Z | - |
dc.date.available | 2023-06-07T02:47:25Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | F1000Research 2022; 11 | en_US |
dc.identifier.issn | 2046-1402 | - |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/33042 | - |
dc.description.abstract | Background: Using the frequentist approach, a recent meta-analysis of three randomized clinical trials in patients undergoing intraoperative ventilation during general anesthesia for major surgery failed to show the benefit of ventilation that uses high positive end-expiratory pressure with recruitment maneuvers when compared to ventilation that uses low positive end-expiratory pressure without recruitment maneuvers. Methods: We designed a protocol for a Bayesian analysis using the pooled dataset. The multilevel Bayesian logistic model will use the individual patient data. Prior distributions will be prespecified to represent a varying level of skepticism for the effect estimate. The primary endpoint will be a composite of postoperative pulmonary complications (PPC) within the first seven postoperative days, which reflects the primary endpoint of the original studies. We preset a range of practical equivalence to assess the futility of the intervention with an interval of odds ratio (OR) between 0.9 and 1.1 and assess how much of the 95% of highest density interval (HDI) falls between the region of practical equivalence. Ethics and dissemination: The used data derive from approved studies that were published in recent years. The findings of this current analysis will be reported in a new manuscript, drafted by the writing committee on behalf of the three research groups. All investigators listed in the original trials will serve as collaborative authors. | en_US |
dc.language.iso | eng | - |
dc.subject | Bayesian analysis | en_US |
dc.subject | Mechanical ventilation | en_US |
dc.subject | PEEP | en_US |
dc.subject | intraoperative ventilation | en_US |
dc.subject | postoperative pulmonary complications | en_US |
dc.subject | recruitment maneuvers | en_US |
dc.title | Effect of intraoperative PEEP with recruitment maneuvers on the occurrence of postoperative pulmonary complications during general anesthesia--protocol for Bayesian analysis of three randomized clinical trials of intraoperative ventilation. | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journaltitle | F1000Research | en_US |
dc.identifier.affiliation | Anesthesiology, Hospital Universitario y Politécnico la Fe, Valencia, Spain, 46026, Spain.;Perioperative Medicine, Instituto de Investigación Sanitaria la Fe, Valencia, Spain, 46026, Spain. | en_US |
dc.identifier.affiliation | Academic Research Organization, Albert Einstein Hospital, Sao Paulo, Brazil. | en_US |
dc.identifier.affiliation | Surgical sciences and integrated diagnostics, University of Genoa, Genoa, Italy.;IRCCS Policlinico San Martino, Genoa, Italy. | en_US |
dc.identifier.affiliation | Critical Care Medicine, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.;Cardio pulmonary department, Instituto do Coração, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidad de de Sao Paulo, Sao Paulo, Brazil. | en_US |
dc.identifier.affiliation | Pulmonary Engineergin group, Anesthesiology and intensive Care, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. | en_US |
dc.identifier.affiliation | Intensive Care, Amsterdam University Medical Centers, location 'AMC', Amsterdam, The Netherlands.;Anesthesiology, Amsterdam University Medical Centers, location 'AMC', Amsterdam, The Netherlands. | en_US |
dc.identifier.affiliation | Anesthesiology and Critical Care, Hospital Clinic de Barcelona, Institut D'investigació August Pi i Sunyer, Barcelona, Spain.;CIBER (Center of Biomedical Research in Respiratory Diseases, Instituto de Salud Carlos III, Madrid, Spain. | en_US |
dc.identifier.affiliation | Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Pamplona, Spain. | en_US |
dc.identifier.affiliation | INCLIVA Clinical Research Institute, Hospital Clinico Universitario de Valencia, Valencia, Spain. | en_US |
dc.identifier.affiliation | Surgical sciences and integrated diagnostics, University of Genoa, Genoa, Italy.;IRCCS Policlinico San Martino, Genoa, Italy. | en_US |
dc.identifier.affiliation | Pulmonary Engineergin group, Anesthesiology and intensive Care, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. | en_US |
dc.identifier.affiliation | Intensive Care, Amsterdam University Medical Centers, location 'AMC', Amsterdam, The Netherlands.;Mahidol Oxford Tropical Medicine Research Unit (MORU), Faculty of tropical medicine, Mahidol University, Bangkok, Thailand.;Nuffield Department of Medicine, University of Oxford, Oxford, UK. | en_US |
dc.identifier.affiliation | Critical Care Medicine, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.;Cardio pulmonary department, Instituto do Coração, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidad de de Sao Paulo, Sao Paulo, Brazil.;Intensive Care, Amsterdam University Medical Centers, location 'AMC', Amsterdam, The Netherlands. | en_US |
dc.identifier.affiliation | Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Australia. | en_US |
dc.identifier.affiliation | Critical | en_US |
dc.identifier.affiliation | Medicine (University of Melbourne) | en_US |
dc.identifier.doi | 10.12688/f1000research.125861.1 | en_US |
dc.type.content | Text | en_US |
dc.identifier.orcid | 0000-0001-7377-331X | en_US |
dc.identifier.pubmedid | 37234075 | - |
dc.description.volume | 11 | - |
dc.description.startpage | 1090 | - |
dc.subject.meshtermssecondary | Positive-Pressure Respiration/adverse effects | - |
dc.subject.meshtermssecondary | Positive-Pressure Respiration/methods | - |
dc.subject.meshtermssecondary | Postoperative Complications/etiology | - |
dc.subject.meshtermssecondary | Postoperative Complications/epidemiology | - |
dc.subject.meshtermssecondary | Anesthesia, General/adverse effects | - |
dc.subject.meshtermssecondary | Anesthesia, General/methods | - |
local.name.researcher | Serpa Neto, Ary | |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.openairetype | Journal Article | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Intensive Care | - |
crisitem.author.dept | Data Analytics Research and Evaluation (DARE) Centre | - |
Appears in Collections: | Journal articles |
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