Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/33028
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dc.contributor.authorBellomo, Rinaldo-
dc.contributor.authorRonco, Claudio-
dc.date2023-
dc.date.accessioned2023-06-07T02:47:19Z-
dc.date.available2023-06-07T02:47:19Z-
dc.date.issued2023-06-01-
dc.identifier.citationContributions to Nephrology 2023; 200en_US
dc.identifier.issn1662-2782-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/33028-
dc.description.abstractThe Jafron series of sorbent cartridges provides a comprehensive array of coated, highly biocompatible sorbent beads made of styrene-divinylbenzene copolymers. Such beads carry a mean diameter of 0.8 mm with a range from 0.60 to 1.18 mm. The maximal pore size of these coated beads and the volume of the cartridge vary according to the type of cartridge ranging between 50 Da and 60 kDa. The sorbents, the size of the cartridge, the volume of sorbent, and the pore size (which reaches 60 kDa with the HA330 cartridge) aim to take advantage of the principles of molecular adsorption in a variety of diseases from uremic toxin retention to poisoning and drug overdose, from kidney disease to liver failure, from acute respiratory distress syndrome to sepsis, from toxic skin injury to COVID-19. The preliminary data from ex vivo studies, animal investigations, and human pilot work look promising and justify a program of systematic investigation of these products to advance our understanding of how they may be incorporated into our therapeutic arsenal.en_US
dc.language.isoeng-
dc.titleClinical Applications of Adsorption: The New Era of Jafron Sorbents.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleContributions to Nephrologyen_US
dc.identifier.affiliationDepartment of Critical Care, School of Medicine, The University of Melbourne, Parkville, Melbourne, Victoria, Australiaen_US
dc.identifier.affiliationInternational Renal Research Institute, Vicenza, Italyen_US
dc.identifier.affiliationAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australiaen_US
dc.identifier.affiliationData Analytics Research and Evaluation (DARE) Centreen_US
dc.identifier.affiliationIntensive Careen_US
dc.identifier.affiliationDepartment of Intensive Care, Royal Melbourne Hospital, Melbourne, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Nephrology, San Bortolo Hospital, Vicenza, Italy.en_US
dc.identifier.doi10.1159/000529845en_US
dc.type.contentTexten_US
dc.identifier.pubmedid37263197-
dc.description.volume200-
dc.description.startpage1-
dc.description.endpage7-
local.name.researcherBellomo, Rinaldo-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
crisitem.author.deptIntensive Care-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
Appears in Collections:Journal articles
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