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dc.contributor.authorCorda, Jennifer-
dc.contributor.authorE Holland, Anne-
dc.contributor.authorBerry, Cassidy Du-
dc.contributor.authorWestrupp, Nicole-
dc.contributor.authorCox, Narelle S-
dc.identifier.citationPediatric Pulmonology 2023; 58(8)en_US
dc.description.abstractTo evaluate the validity and reliability of the modified shuttle 25-level test (MST-25) in children with cystic fibrosis (CF). A prospective single center study in clinically stable children with CF. Participants undertook two testing conditions on different days: (1) 2xMST-25 tests; (2) cardiopulmonary exercise test (CPET). Test order was randomized. Nadir oxygen saturation (SpO2 ), peak heart rate (HR), breathlessness (modified Borg), rate of perceived exertion (RPE), energy expenditure (EE) and metabolic equivalents (MET) from the MST-25 and CPET were compared to assess validity, while outcomes from 2xMST-25 tests were compared for reliability. CPET was performed using breath-by-breath analysis and EE from the MST-25 obtained using the SenseWear Armband. Strong correlations were found between MST-25 distance and peak oxygen uptake, peak work and minute ventilation on CPET (all r > 0.7, p < 0.01). Moderate correlations were found between MST-25 distance and CPET for METs (r = 0.5) and HR (r = 0.6). Weak associations between tests were evident for nadir SpO2 (r = 0.1), modified Borg (rs  = 0.2) and RPE (rs  = 0.2). Test-retest reliability was excellent for MST-25 distance (ICC 0.91), peak EE (ICC 0.99) and peak METs (ICC 0.90). Good reliability was achieved for HR (ICC 0.84) and modified Borg score (ICC 0.77), while moderate reliability for nadir SpO2 (ICC 0.64) and RPE (ICC 0.68) was observed. The MST-25 is a valid and reliable field test for the assessment of exercise capacity in children with CF. The MST-25 can be used to accurately monitor exercise capacity and prescribe exercise training, particularly when CPET is not available.en_US
dc.subjectcystic fibrosisen_US
dc.subjectexercise testingen_US
dc.subjectexercise toleranceen_US
dc.subjectfield testsen_US
dc.titleValidation of the 25 level modified shuttle test in children with cystic fibrosis.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitlePediatric Pulmonologyen_US
dc.identifier.affiliationDepartment of Physiotherapy, Royal Children's Hospital, Melbourne, Australiaen_US
dc.identifier.affiliationRespiratory Research@Alfred, Monash University, Melbourne, Australia.en_US
dc.identifier.affiliationDepartment of Respiratory and Sleep Medicine, Royal Children's Hospital, Melbourne, Australia.;Infection and Immunity group, Murdoch Children's Research Institute, Melbourne, Australia.;Department of Paediatrics, University of Melbourne, Melbourne, Australia.en_US
dc.identifier.affiliationInfection and Immunity group, Murdoch Children's Research Institute, Melbourne, Australia.en_US
dc.identifier.affiliationInstitute for Breathing and Sleepen_US
dc.identifier.affiliationDepartment of Physiotherapy, La Trobe University, Melbourne, Australia.en_US
dc.identifier.affiliationDepartment of Physiotherapy, Alfred Health, Melbourne, Australia.en_US
dc.identifier.pubmedid37144876-, Narelle S
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.languageiso639-1en- for Breathing and Sleep-
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