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https://ahro.austin.org.au/austinjspui/handle/1/32348| Title: | Spin and fragility in anaesthesia studies: when sirens sing into anaesthetists' ears. | Austin Authors: | Gama de Abreu, Marcelo;Schultz, Marcus J;Serpa Neto, Ary | Affiliation: | Department of Outcomes Research, Cleveland, OH, USA; Department of Intensive Care and Resuscitation, Cleveland, OH, USA; Department of Cardiothoracic Anesthesiology, Cleveland Clinic, Cleveland, OH, USA; Department of Anesthesiology and Intensive Care, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany. Department of Intensive Care, Amsterdam University Medical Centre, Location AMC, Amsterdam, the Netherlands; Mahidol-Oxford Tropical Medicine Research Unit (MORU), Mahidol University, Bangkok, Thailand; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Critical Care, Department of Critical Care Medicine, Hospital Israelita Albert Einstein, Sao Paulo, Brazil Intensive Care University of Melbourne Clinical School |
Issue Date: | 15-Mar-2023 | Date: | 2023 | Publication information: | British Journal of Anaesthesia 2023; 130(5) | Abstract: | Spin and fragility are common in randomised controlled trials published in anaesthesia journals. Staying with the facts and addressing only the primary endpoint in the conclusion of clinical research reports might help reduce spin. Routinely reporting the fragility index, in turn, could deliver information about robustness, enhancing the transparency of positive dichotomous results. It is in the best interest of clinical research that authors, reviewers, and journals come together to reduce spin and address the fragility of randomised controlled trials. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/32348 | DOI: | 10.1016/j.bja.2023.02.021 | ORCID: | Journal: | British Journal of Anaesthesia | PubMed URL: | 36931963 | ISSN: | 1471-6771 | Type: | Journal Article | Subjects: | binary outcomes fragility randomised controlled trial robustness spin trial design |
| Appears in Collections: | Journal articles |
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