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https://ahro.austin.org.au/austinjspui/handle/1/31637| Title: | Disease Reactivation After Cessation of Disease-Modifying Therapy in Patients With Relapsing-Remitting Multiple Sclerosis. | Austin Authors: | Roos, Izanne;Malpas, Charles;Leray, Emmanuelle;Casey, Romain;Horakova, Dana;Havrdova, Eva Kubala;Debouverie, Marc;Patti, Francesco;De Seze, Jerome;Izquierdo, Guillermo;Eichau, Sara;Edan, Gilles;Prat, Alexandre;Girard, Marc;Ozakbas, Serkan;Grammond, Pierre;Zephir, Helene;Ciron, Jonathan;Maillart, Elisabeth;Moreau, Thibault;Amato, Maria Pia;Labauge, Pierre;Alroughani, Raed;Buzzard, Katherine;Skibina, Olga;Terzi, Murat;Laplaud, David Axel;Berger, Eric;Grand'Maison, Francois;Lebrun-Frenay, Christine;Cartechini, Elisabetta;Boz, Cavit;Lechner-Scott, Jeannette;Clavelou, Pierre;Stankoff, Bruno;Prevost, Julie;Kappos, Ludwig;Pelletier, Jean;Shaygannejad, Vahid;Yamout, Bassem I;Khoury, Samia J;Gerlach, Oliver;Spitaleri, Daniele L A;Van Pesch, Vincent;Gout, Olivier;Turkoglu, Recai;Heinzlef, Olivier;Thouvenot, Eric;McCombe, Pamela Ann;Soysal, Aysun;Bourre, Bertrand;Slee, Mark;Castillo-Trivino, Tamara;Bakchine, Serge;Ampapa, Radek;Butler, Ernest Gerard;Wahab, Abir;Macdonell, Richard A L ;Aguera-Morales, Eduardo;Cabre, Philippe;Ben, Nasr Haifa;Van der Walt, Anneke;Laureys, Guy;Van Hijfte, Liesbeth;Ramo-Tello, Cristina M;Maubeuge, Nicolas;Hodgkinson, Suzanne;Sánchez-Menoyo, José Luis;Barnett, Michael H;Labeyrie, Celine;Vucic, Steve;Sidhom, Youssef;Gouider, Riadh;Csepany, Tunde;Sotoca, Javier;de Gans, Koen;Al-Asmi, Abdullah;Fragoso, Yara Dadalti;Vukusic, Sandra;Butzkueven, Helmut;Kalincik, Tomas | Affiliation: | From the CORe (I.R., C.M., T.K.), Department of Medicine, University of Melbourne, Australia Melbourne MS Centre (I.R., C.M., T.K.), Department of Neurology, Royal Melbourne Hospital, Australia Rennes, University (E.L.), EHESP, REPERES EA 7449, France; Univ Rennes (E.L.), CHU Rennes, Inserm, CIC 1414 ([Centre d'Investigation Clinique de Rennes]), France Université de Lyon (R.C.), Université Claude Bernard Lyon 1, France Hospices Civils de Lyon (R.C.), Service de Neurologie, Sclérose en Plaques, Pathologies de La Myéline et Neuro-inflammation, Bron, France Observatoire Français de La Sclérose en Plaques (R.C.), Centre de Recherche en Neurosciences de Lyon, INSERM 1028 et CNRS UMR 5292, France Eugène Devic EDMUS Foundation Against Multiple Sclerosis (R.C.), State-approved Foundation, Bron, France Department of Neurology, Royal Melbourne Hospital, Australia Department of Neurology and Center of Clinical Neuroscience (D.H., E.K.H.), First Faculty of Medicine, Charles University in Prague and General University Hospital, Czech Republic Nancy University Hospital (M.D.), Department of Neurology, Nancy, France Department of Medical and Surgical Sciences and Advanced Technologies (F.P.), GF Ingrassia, Catania, Italy; Multiple Sclerosis Center (F.P.), University of Catania, Italy; CHU de Strasbourg (J.D.S.), Department of Neurology and Clinical Investigation Center, CIC 1434, INSERM 1434, Strasbourg, France; Hospital Universitario Virgen Macarena (G.I., S.E.), Sevilla, Spain; CHU Pontchaillou (G.E.), CIC1414 INSERM, Rennes, France; CHUM MS Center and Universite de Montreal (A.P., M.G.), Canada; Dokuz Eylul University (S.O.), Konak/Izmir, Turkey; CISSS Chaudière-Appalache (P.G.), Levis, Canada; CHU Lille (H.Z.), CRCSEP Lille, Univ Lille, U1172, France; CHU de Toulouse (J.C.), Hôpital Pierre-Paul Riquet, Department of Neurology, CRC-SEP, France; Département de Neurologie (E.M.), Hôpital Pitié-Salpêtrière, APHP, Paris; CHU de Dijon (T.M.), Department of Neurology, EA4184, France; Department NEUROFARBA (M.P.A.), University of Florence, Italy; CHU de Montpellier (P.L.), MS Unit, France; University of Montpellier (MUSE) (P.L.), France; Division of Neurology (Raed Alroughani), Department of Medicine, Amiri Hospital, Sharq, Kuwait; Department of Neurology (K.B., O.S.), Box Hill Hospital, Melbourne, Australia| Monash University (K.B., O.S.), Melbourne, Australia| Melbourne MS Centre (K.B.), Royal Melbourne Hospital, Australia| The Alfred Hospital (O.S.), Melbourne, Australia| Medical Faculty (M.T.), 19 Mayis University, Samsun, Turkey; CHU de Nantes (D.A.L.), Service de Neurologie & CIC015 INSERM, France; CRTI-Inserm U1064 (D.A.L.), Nantes, France; CHU de Besançon (E.B.), Service de Neurologie 25 030 Besançon, France; Neuro Rive-Sud (F.G.M.), Quebec, Canada; Neurology (C.L.-F.), UR2CA, Centre Hospitalier Universitaire Pasteur2, Université Nice Côte d'Azur, Nice, France; UOC Neurologia (E.C.), Azienda Sanitaria Unica Regionale Marche-AV3, Macerata, Italy; KTU Medical Faculty Farabi Hospital (C.B.), Trabzon, Turkey; School of Medicine and Public Health (J.L.-S.), University Newcastle, Australia| Department of Neurology (J.L.-S.), John Hunter Hospital, Hunter New England Health, Newcastle, Australia| CHU Clermont-Ferrand (Pierre Clavelou), Department of Neurology; Université Clermont Auvergne, Inserm, Neuro-Dol, Clermont-Ferrand, France; Sorbonne Universités (B.S.), UPMC Paris 06, Brain and Spine Institute, ICM, Hôpital de La Pitié Salpêtrière, Inserm UMR S 1127, CNRS UMR 7225, and Department of Neurology, AP-HP, Saint-Antoine Hospital, Paris, France; CSSS Saint-Jérôme (Julie Prevost), Saint-Jerome, Canada; Neurologic Clinic and Policlinic (L.K.), Departments of Medicine and Clinical Research, University Hospital and University of Basel, Switzerland; Aix Marseille Univ (Jean Pelletier), APHM, Hôpital de La Timone, Pôle de Neurosciences Cliniques, Service de Neurologie, France; Isfahan University of Medical Sciences (V.S.), Iran; Nehme and Therese Tohme Multiple Sclerosis Center (B.I.Y., S.J.K.), American University of Beirut Medical Center, Beirut, Lebanon; Department of Neurology (Oliver Gerlach), Zuyderland Medical Center, Sittard-Geleen, Netherlands; Azienda Ospedaliera di Rilievo Nazionale San Giuseppe Moscati Avellino (D.L.A.S.), Italy; Cliniques Universitaires Saint-Luc (V.V.P.), Université Catholique de Louvain, Brussels, Belgium; Fondation Rotschild (Olivier Gout), Department of Neurology, Paris, France; Haydarpasa Numune Training and Research Hospital (R.T.), Istanbul, Turkey; Hôpital de Poissy (O.H.), Department of Neurology, France; Department of Neurology (E.T.), Nimes University Hospital, France; Institut de Génomique Fonctionnelle (E.T.), UMR5203, INSERM 1191, Univ. Montpellier, France; University of Queensland (P.A.M.), Brisbane, Australia| Royal Brisbane and Women's Hospital (P.A.M.), Australia| Bakirkoy Education and Research Hospital for Psychiatric and Neurological Diseases (A.S.), Istanbul, Turkey; CHU de Rouen (B.B.), Department of Neurology, France; Flinders University (M.S.), Adelaide, Australia| Instituto de Investigación Sanitaria Biodonostia (T.C.-T.), Hospital Universitario Donostia, San Sebastián, Spain; CHU de Reims (S.B.), Department of Neurology, France; Nemocnice Jihlava (Radek Ampapa), Czech Republic; Monash Medical Centre (E.G.B.), Melbourne, Australia| APHP (A.W.), Hôpital Henri Mondor, Department of Neurology, Créteil, France; Austin Health (R.A.M.), Melbourne, Australia| University Hospital Reina Sofia (E.A.-M.), Cordoba, Spain; CHU de La Martinique (Philippe Cabre), Department of Neurology, Fort-de-France, France; Hôpital Sud Francilien (N.H.B.), Department of Neurology, Corbeil Essonnes, France; Department of Neurology (A.V.W., H.B.), The Alfred Hospital, Melbourne, Australia| Central Clinical School (A.V.W., H.B.), Monash University, Melbourne, Australia| Department of Neurology (G.L., L.V.H.), University Hospital Ghent, Belgium; Hospital Germans Trias I Pujol (C.M.R.-T.), Badalona, Spain; CHU La Milétrie (N.M.), Hôpital Jean Bernard, Department of Neurology, Poitiers, France; Liverpool Hospital (S.H.), Sydney, Australia| Hospital de Galdakao-Usansolo (J.L.S.-M.), Spain; Brain and Mind Centre (M.H.B.), Sydney, Australia| CHU Bicêtre (C.L.), Department of Neurology, F-94275 Le Kremlin Bicêtre, France; Westmead Hospital (Steve Vucic), Sydney, Australia| Department of Neurology (Y.S., R.G.), Razi Hospital, Manouba, Tunisia; Department of Neurology (T.C.), Faculty of Medicine, University of Debrecen, Hungary; Hospital Universitari MútuaTerrassa (J.S.), Barcelona, Spain; Groene Hart Ziekenhuis (K.G.), Gouda, Netherlands; Sultan Qaboos University Hospital (A.A.-A.), Al-Khodh, Oman; Universidade Metropolitana de Santos (Y.D.F.), Santos, Brazil; Service de Neurologie (Sandra Vukusic), Sclérose en Plaques, Pathologies de La Myéline et Neuro-inflammation, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France; Centre des Neurosciences de Lyon (Sandra Vukusic), Observatoire Français de La Sclérose en Plaques, INSERM 1028 et CNRS UMR5292, France; and Université Claude Bernard Lyon 1 (Sandra Vukusic), Faculté de Médecine Lyon Est, France. Multiple Sclerosis Center, University of Catania, Catania, Italy CHU de Strasbourg, Department of Neurology and Clinical Investigation Center, CIC 1434, INSERM 1434, Strasbourg, France Hospital Universitario Virgen Macarena, Sevilla, Spain CHU Pontchaillou, CIC1414 INSERM, Rennes France CHUM MS Center and Universite de Montreal, Montreal, Canada Dokuz Eylul University, Konak/Izmir, Turkey CISSS Chaudi`ereAppalache, Levis, Canada CHU Lille, CRCSEP Lille, Univ Lille, U1172, Lille, France CHU de Toulouse, Hˆ opital Pierre-Paul Riquet, Department of Neurology, CRC-SEP, Toulouse Cedex 9, France D´epartement de neurologie, Hopital Piti ˆ ´eSalpˆetri`ere, APHP, Paris CHU de Dijon, Department of Neurology, EA4184, Dijon, France Department NEUROFARBA, University of Florence, Florence, Italy CHU de Montpellier, MS Unit, Montpellier Cedex 5, France; University of Montpellier (MUSE), Montpellier, France Division of Neurology, Department of Medicine, Amiri Hospital, Sharq, Kuwait Department of Neurology, Box Hill Hospital, Melbourne, Australia Monash University, Melbourne, Australia Melbourne MS Centre, Royal Melbourne Hospital, Melbourne, Australia The Alfred Hospital, Melbourne, Australia Medical Faculty, 19 Mayis University, Samsun, Turkey CHU de Nantes, Service de Neurologie & CIC015 INSERM, Nantes, France CRTI-Inserm U1064, Nantes, France CHU de Besançon, Service de Neurologie 25 030 Besançon, France Neuro Rive-Sud, Quebec, Canada Neurology, UR2CA, Centre Hospitalier Universitaire Pasteur2, Universit´e Nice Cote d ˆ ’Azur, Nice, France UOC Neurologia, Azienda Sanitaria Unica Regionale Marche–AV3, Macerata, Italy KTU Medical Faculty Farabi Hospital, Trabzon, Turkey School of Medicine and Public Health, University Newcastle, Newcastle, Australia Department of Neurology, John Hunter Hospital, Hunter New England Health, Newcastle, Australia CHU Clermont-Ferrand, Department of Neurology, Clermont-Ferrand Universit´e Clermont Auvergne, Inserm, NeuroDol, Clermont-Ferrand, France Sorbonne Universit´es, UPMC Paris 06, Brain and Spine Institute, ICM, Hopital ˆ de la Piti´e Salpˆetri`ere, Inserm UMR S 1127, CNRS UMR 7225 Department of Neurology, AP-HP, Saint-Antoine hospital, Paris, France CSSS Saint-J´erome, Saint- ˆ Jerome, Canada Neurologic Clinic and Policlinic, Departments of Medicine and Clinical Research, University Hospital and University of Basel, Basel, Switzerland Aix Marseille Univ, APHM, Hopital de la Timone, P ˆ ole ˆ de Neurosciences Cliniques, Service de Neurologie, 13005 Marseille, France Isfahan University of Medical Sciences, Isfahan, Iran Nehme and Therese Tohme Multiple Sclerosis Center, American University of Beirut Medical Center, Beirut, Lebanon Department of Neurology, Zuyderland Medical Center, Sittard-Geleen, Netherlands Azienda Ospedaliera di Rilievo Nazionale San Giuseppe Moscati Avellino, Avellino, Italy Cliniques Universitaires Saint-Luc, Universit´e Catholique de Louvain, Brussels, Belgium Fondation Rotschild, Department of Neurology, Paris, France Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey Hˆ opital de Poissy, Department of Neurology, Poissy, France Department of Neurology, Nimes University Hospital, Nimes Cedex 9, France Institut de G´enomique Fonctionnelle, UMR5203, INSERM 1191, Univ. Montpellier, Montpellier Cedex 5, France University of Queensland, Brisbane, Australia Royal Brisbane and Women’s Hospital, Brisbane, Australia Bakirkoy Education and Research Hospital for Psychiatric and Neurological Diseases, Istanbul, Turkey CHU de Rouen, Department of Neurology, Rouen, France Flinders University, Adelaide, Australia Instituto de Investigacion´ Sanitaria Biodonostia, Hospital Universitario Donostia, San Sebasti´an, Spain CHU de Reims, Department of Neurology, Reims cedex, France Nemocnice Jihlava, Jihlava, Czech Republic Monash Medical Centre, Melbourne, Australia APHP, Hˆ opital Henri Mondor, Department of Neurology, Cr´eteil, France Austin Health University Hospital Reina Sofia, Cordoba, Spain CHU de la Martinique, Department of Neurology, Fort-de-France, Franc Hopital Sud Francilien, ˆ Department of Neurology, Corbeil Essonnes, France Department of Neurology, The Alfred Hospital, Melbourne Central Clinical School, Monash University, Melbourne, Australia Department of Neurology, University Hospital Ghent, Ghent, Belgium Hospital Germans Trias i Pujol, Badalona, Spain CHU La Mil´etrie, Hˆ opital Jean Bernard, Department of Neurology, Poitiers, France Liverpool Hospital, Sydney, Australia Hospital de GaldakaoUsansolo, Galdakao, Spain Brain and Mind Centre, Sydney, Australia CHU Bicˆetre, Department of Neurology, Le Kremlin Bicˆetre, France Westmead Hospital, Sydney, Australia Department of Neurology, Razi Hospital, Manouba, Tunisia Department of Neurology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary Hospital Universitari MutuaTerrassa, Barcelona, ´ Spain Groene Hart Ziekenhuis, Gouda, Netherlands Sultan Qaboos University Hospital, Al-Khodh, Oman Universidade Metropolitana de Santos, Santos, Brazil Service de neurologie, scl´erose en plaques, pathologies de la my´eline et neuro-inflammation, Hopital Neurologique ˆ Pierre Wertheimer, Hospices Civils de Lyon, 69677 Lyon/Bron, France Centre des Neurosciences de Lyon, Observatoire Français de la Scl´erose en Plaques, INSERM 1028 et CNRS UMR5292, 69003 Lyon, France Universit´e Claude Bernard Lyon 1, Facult´e de m´edecine Lyon Est, Lyon, France Melbourne MS Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia |
Issue Date: | 25-Oct-2022 | Date: | 2022 | Publication information: | Neurology 2022 | Abstract: | To evaluate the rate of return of disease activity after cessation of multiple sclerosis (MS) disease-modifying therapy. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/31637 | DOI: | 10.1212/WNL.0000000000201029 | ORCID: | 0000-0003-0371-3666 0000-0002-5918-9261 0000-0002-3386-6308 0000-0001-7699-0328 0000-0003-0091-0074 0000-0002-3713-2416 0000-0003-2885-9004 0000-0001-9724-851X 0000-0001-8671-7747 0000-0002-2459-2480 0000-0002-9249-3185 0000-0002-8604-2054 0000-0002-4278-7003 0000-0002-1708-4373 0000-0003-2634-8294 0000-0002-2156-8864 0000-0002-8305-3209 0000-0002-2851-8157 0000-0001-8726-089X 0000-0003-3778-1376 |
Journal: | Neurology | Start page: | e1926 | End page: | e1944 | PubMed URL: | 35977837 | PubMed URL: | https://pubmed.ncbi.nlm.nih.gov/35977837/ | ISSN: | 1526-632X | Type: | Journal Article | Subjects: | Multiple Sclerosis, Relapsing-Remitting/drug therapy Multiple Sclerosis, Relapsing-Remitting/epidemiology Natalizumab/therapeutic use Fingolimod Hydrochloride/therapeutic use Multiple Sclerosis/chemically induced Immunosuppressive Agents/adverse effects |
| Appears in Collections: | Journal articles |
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