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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/31621
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dc.contributor.authorMcMahon, James H-
dc.contributor.authorLau, Jillian S Y-
dc.contributor.authorColdham, Anna-
dc.contributor.authorRoney, Janine-
dc.contributor.authorHagenauer, Michelle-
dc.contributor.authorPrice, Sally-
dc.contributor.authorBryant, Mellissa-
dc.contributor.authorGarlick, Jill-
dc.contributor.authorPaterson, Anne-
dc.contributor.authorLee, Sue J-
dc.contributor.authorO'Bryan, Jess-
dc.contributor.authorHearps, Anna-
dc.contributor.authorTachedjian, Gilda-
dc.contributor.authorPinskier, Henry-
dc.contributor.authorPhillips, Cameron-
dc.contributor.authorGarrow, Stuart-
dc.contributor.authorPinskier, Nathan-
dc.contributor.authorMelvin, Robert-
dc.contributor.authorBlakeway, Luke-
dc.contributor.authorWisniewski, Jessica A-
dc.contributor.authorByers, Sally-
dc.contributor.authorBadoordeen, Gnei Z-
dc.contributor.authorPereira, Stephanie-
dc.contributor.authorPragastis, Katherine-
dc.contributor.authorTrubiano, Jason-
dc.contributor.authorChua, Kyra Y L-
dc.contributor.authorKainer, Marion-
dc.contributor.authorMolton, James S-
dc.contributor.authorGardiner, Bradley J-
dc.contributor.authorPierce, Anna B-
dc.contributor.authorCheng, Allen-
dc.contributor.authorRogers, Benjamin A-
dc.contributor.authorPeleg, Anton Y-
dc.date2022-
dc.date.accessioned2023-01-12T01:38:37Z-
dc.date.available2023-01-12T01:38:37Z-
dc.date.issued2022-12-
dc.identifier.citationEClinicalMedicine 2022; 54en_US
dc.identifier.issn2589-5370-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/31621-
dc.description.abstractWell tolerated antivirals administered early in the course of COVID-19 infection when the viremia is highest could prevent progression to severe disease. Favipiravir inhibits SARS-CoV-2 viral replication in vitro with evidence of clinical benefit in open label trials. Placebo controlled studies of people with early symptomatic COVID-19 with regular assessments of SARS-CoV-2 viral load can determine if it has an antiviral effect and improves clinical outcomes.en_US
dc.language.isoeng-
dc.subjectCOVID-19en_US
dc.subjectFavipiraviren_US
dc.subjectRandomised clinical trialen_US
dc.titleFavipiravir in early symptomatic COVID-19, a randomised placebo-controlled trial.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleEClinicalMedicineen_US
dc.identifier.affiliationDepartment of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.en_US
dc.identifier.affiliationDepartment of Infectious Diseases, Monash Medical Centre, Melbourne, Australia.en_US
dc.identifier.affiliationLife Sciences Discipline, Burnet Institute, Melbourne, Australia.en_US
dc.identifier.affiliationOnsite Doctor and OSD.Care, Melbourne, Australia.en_US
dc.identifier.affiliationDepartment of Emergency Medicine, Alfred Hospital, Melbourne, Australia.en_US
dc.identifier.affiliationDepartment of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.en_US
dc.identifier.affiliationInfectious Diseasesen_US
dc.identifier.affiliationDepartment of Infectious Diseases, Western Health, Melbourne, Australia.en_US
dc.identifier.doi10.1016/j.eclinm.2022.101703en_US
dc.type.contentTexten_US
dc.identifier.pubmedid36284645-
dc.description.volume54-
dc.description.startpage101703-
local.name.researcherChua, Kyra Y L-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptMedicine (University of Melbourne)-
crisitem.author.deptCentre for Antibiotic Allergy and Research-
crisitem.author.deptMicrobiology-
crisitem.author.deptInfectious Diseases-
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