Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/30864
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dc.contributor.authorBeare, Richard-
dc.contributor.authorAlexander, Bonnie-
dc.contributor.authorWarren, Aaron-
dc.contributor.authorKean, Michael-
dc.contributor.authorSeal, Marc-
dc.contributor.authorWray, Alison-
dc.contributor.authorMaixner, Wirginia-
dc.contributor.authorYang, Joseph Yuan-Mou-
dc.date2022-
dc.date.accessioned2022-09-20T06:45:59Z-
dc.date.available2022-09-20T06:45:59Z-
dc.date.issued2023-01-
dc.identifier.citationInternational Journal of Computer Assisted Radiology and Surgery 2023; 18(1)en
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/30864-
dc.description.abstractThe neuroimaging research community-which includes a broad range of scientific, medical, statistical, and engineering disciplines-has developed many tools to advance our knowledge of brain structure, function, development, aging, and disease. Past research efforts have clearly shaped clinical practice. However, translation of new methodologies into clinical practice is challenging. Anything that can reduce these barriers has the potential to improve the rate at which research outcomes can contribute to clinical practice. In this article, we introduce Karawun, a file format conversion tool, that has become a key part of our work in translating advances in diffusion imaging acquisition and analysis into neurosurgical practice at our institution. Karawun links analysis workflows created using open-source neuroimaging software, to Brainlab (Brainlab AG, Munich, Germany), a commercially available surgical planning and navigation suite. Karawun achieves this using DICOM standards supporting representation of 3D structures, including tractography streamlines, and thus offers far more than traditional screenshot or color overlay approaches. We show that neurosurgical planning data, created from multimodal imaging data using analysis methods implemented in open-source research software, can be imported into Brainlab. The datasets can be manipulated as if they were created by Brainlab, including 3D visualizations of white matter tracts and other objects. Clinicians can explore and interact with the results of research neuroimaging pipelines using familiar tools within their standard clinical workflow, understand the impact of the new methods on their practice and provide feedback to methods developers. This capability has been important to the translation of advanced analysis techniques into practice at our institution.en
dc.language.isoeng-
dc.subjectDICOMen
dc.subjectDiffusion imagingen
dc.subjectImage-guided surgeryen
dc.subjectTractographyen
dc.titleKarawun: a software package for assisting evaluation of advances in multimodal imaging for neurosurgical planning and intraoperative neuronavigation.en
dc.typeJournal Articleen
dc.identifier.journaltitleInternational Journal of Computer Assisted Radiology and Surgeryen
dc.identifier.affiliationNeuroscience Research, Murdoch Children's Research Institute, Melbourne, Australiaen
dc.identifier.affiliationThe Florey Institute of Neuroscience and Mental Healthen
dc.identifier.affiliationMedical Imaging, The Royal Children's Hospital, Melbourne, Australiaen
dc.identifier.affiliationDepartment of Paediatrics, The University of Melbourne, Melbourne, Australiaen
dc.identifier.affiliationDevelopmental Imaging, Murdoch Children's Research Institute, Melbourne, Australiaen
dc.identifier.affiliationNational Centre for Healthy Ageing, Melbourne, Australiaen
dc.identifier.affiliationPeninsula Clinical School, Central Clinical School, Monash University, Frankston, Australiaen
dc.identifier.affiliationDepartment of Neurosurgery, Neuroscience Advanced Clinical Imaging Service (NACIS), The Royal Children's Hospital, Melbourne, Australiaen
dc.identifier.affiliationMedicine (University of Melbourne)en
dc.identifier.doi10.1007/s11548-022-02736-7en
dc.type.contentTexten
dc.identifier.orcidhttp://orcid.org/0000-0002-7530-5664en
dc.identifier.pubmedid36070033-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
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