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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/30711
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dc.contributor.authorvan Vliet, Erwin A-
dc.contributor.authorHildebrand, Michael S-
dc.contributor.authorMills, James D-
dc.contributor.authorBrennan, Gary P-
dc.contributor.authorEid, Tore-
dc.contributor.authorMasino, Susan A-
dc.contributor.authorWhittemore, Vicky-
dc.contributor.authorBindila, Laura-
dc.contributor.authorWang, Kevin K-
dc.contributor.authorPatel, Manisha-
dc.contributor.authorPerucca, Piero-
dc.contributor.authorReid, Christopher A-
dc.date2022-
dc.date.accessioned2022-08-16T06:57:54Z-
dc.date.available2022-08-16T06:57:54Z-
dc.date.issued2022-08-11-
dc.identifier.citationEpilepsia Open 2022; online first: 11 Augusten
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/30711-
dc.description.abstractThe International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines. The aim of the CDEs is to improve the standardization of experimental designs across a range of epilepsy research related methods. Here, we have generated CDE tables with key parameters and case report forms (CRFs) containing the essential contents of the study protocols for genomics, transcriptomics and epigenomics in rodent models of epilepsy, with a specific focus on adult rats and mice. We discuss the important elements that need to be considered for genomics, transcriptomics and epigenomics methodologies, providing a rationale for the parameters that should be collected. This is the first in a two-part series of omics papers with the second instalment to cover proteomics, lipidomics, and metabolomics in adult rodents.en
dc.language.isoeng
dc.subjectcommon data elementsen
dc.subjectmouseen
dc.subjectomic data processingen
dc.subjectpreclinicalen
dc.subjectraten
dc.titleA companion to the preclinical common data elements for genomics, transcriptomics and epigenomics data in rodent epilepsy models. A Report of the TASK3-WG4 Omics Working Group of the ILAE/AES Joint Translational Task Force.en
dc.typeJournal Articleen_US
dc.identifier.journaltitleEpilepsia Openen
dc.identifier.affiliationThe Florey Institute of Neuroscience and Mental Healthen
dc.identifier.affiliationCenter for Neuroscience, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, the Netherlands..en
dc.identifier.affiliationEpilepsy Research Centreen
dc.identifier.affiliationMurdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia..en
dc.identifier.affiliationComprehensive Epilepsy Programen
dc.identifier.affiliationDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia..en
dc.identifier.affiliationDepartments of Neurology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia..en
dc.identifier.affiliationDepartment of Neurology, Alfred Health, Melbourne, Victoria, Australia..en
dc.identifier.affiliationAmsterdam UMC, University of Amsterdam, Dept (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, the Netherlands..en
dc.identifier.affiliationUCD School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Dublin, Ireland..en
dc.identifier.affiliationDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA..en
dc.identifier.affiliationNeuroscience Program and Psychology Department, Life Sciences Center, Trinity College, Hartford, Connecticut, USA..en
dc.identifier.affiliationDivision of Neuroscience, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA..en
dc.identifier.affiliationClinical Lipidomics Unit, Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University of Mainz, Mainz, Germany..en
dc.identifier.affiliationDepartment of Emergency Medicine, Psychiatry and Neuroscience, University of Florida, Gainesville, Florida, USA..en
dc.identifier.affiliationDepartment of Pharmaceutical Sciences, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA..en
dc.identifier.affiliationAmsterdam UMC, University of Amsterdam, Dept (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, the Netherlands..en
dc.identifier.affiliationFutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland..en
dc.identifier.affiliationEpilepsy Genetics Program, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA..en
dc.identifier.affiliationBrain Rehabilitation Research Center, Malcom Randall VA Medical Center, North Florida/South Georgia Veterans Health System, Gainesville, Florida, USA..en
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/35950645/en
dc.identifier.doi10.1002/epi4.12640en
dc.type.contentTexten_US
dc.identifier.orcid0000-0001-5747-3202en
dc.identifier.orcid0000-0001-9217-6393en
dc.identifier.orcid0000-0003-4237-4900en
dc.identifier.orcid0000-0002-7855-7066en
dc.identifier.orcid0000-0002-1457-8028en
dc.identifier.orcid0000-0003-2739-0515en
dc.identifier.pubmedid35950645
local.name.researcherHildebrand, Michael S
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
crisitem.author.deptEpilepsy Research Centre-
crisitem.author.deptMedicine (University of Melbourne)-
crisitem.author.deptNeurology-
crisitem.author.deptComprehensive Epilepsy Program-
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