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Title: Cardiovascular Disease in Adult Cancer Survivors: a Review of Current Evidence, Strategies for Prevention and Management, and Future Directions for Cardio-oncology.
Austin Authors: Muhandiramge, Jaidyn;Zalcberg, John R;van Londen, G J;Warner, Erica T;Carr, Prudence R;Haydon, Andrew;Orchard, Suzanne G
Affiliation: Department of Medical Oncology, Alfred Hospital, Melbourne, VIC, Australia..
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, VIC, 3004, Australia..
Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA..
Clinical and Translational Epidemiology Unit, MGH Cancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA..
Austin Health
Issue Date: 7-Jul-2022
Date: 2022
Publication information: Current Oncology Reports 2022; 24(11)
Abstract: Cardiovascular disease is long-term complication of both cancer and anti-cancer treatment and can have significant ramifications for health-related quality of life and mortality. This narrative review explores the current evidence linking cardiovascular disease and cancer, as well as exploring strategies for the prevention and management of cardiovascular disease, and outlines future opportunities in the field of cardio-oncology. Cancer confers risk for various cardiovascular diseases including heart failure, cardiomyopathy, arrhythmia, coronary heart disease, stroke, venous thromboembolism, and valvular heart disease. Cancer treatment, in particular agents such as platinum-based chemotherapy, anthracyclines, hormonal treatments, and thoracic radiotherapy, further increases risk. While cardiovascular disease can be identified early and effectively managed in cancer survivors, cardiovascular screening and management does not typically feature in routine long-term cancer care of adult cancer survivors. Cancer and cancer treatment can accelerate the development of cardiovascular disease. Further research into screening and management strategies for cardiovascular disease, along with evidence-based guidelines, is required to ensure adult cancer survivors receive appropriate long-term care.
DOI: 10.1007/s11912-022-01309-w
Journal: Current oncology reports
PubMed URL: 35796941
PubMed URL:
Type: Journal Article
Subjects: Aging
Cardiovascular disease
Heart failure
Myocardial infarction
Appears in Collections:Journal articles

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