Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/30055
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dc.contributor.authorRay, Jason C-
dc.contributor.authorPham, Xiuxian-
dc.contributor.authorFoster, Emma-
dc.contributor.authorCheema, Sanjay-
dc.contributor.authorCorcoran, Susan J-
dc.contributor.authorMatharu, Manjit S-
dc.contributor.authorHutton, Elspeth J-
dc.date2022-
dc.date.accessioned2022-06-22T06:51:19Z-
dc.date.available2022-06-22T06:51:19Z-
dc.date.issued2022-04-25-
dc.identifier.citationCephalalgia : An International Journal of Headache 2022; 42(11-12): 1274-1287en
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/30055-
dc.description.abstractHeadache is a common presentation of postural tachycardia syndrome, yet robust prevalence data is lacking. To undertake a systematic review and meta-analysis to estimate the prevalence of headache disorders in postural tachycardia syndrome, and to explore the potential shared pathophysiological mechanisms that underpin these conditions as well as treatment options. Three databases were searched for publications evaluating prevalence of migraine (primary outcome) and general and orthostatic headache (secondary outcomes) in patients with postural tachycardia syndrome. Two independent reviewers selected studies and extracted data. A random-effects meta-analysis calculated the pooled prevalence of migraine in postural tachycardia syndrome. A narrative literature review explored the pathophysiology and treatment options for concurrent headache disorders and postural tachycardia syndrome. Twenty-three articles met inclusion criteria. Estimated pooled prevalence of migraine in postural tachycardia syndrome was 36.8% (95% CI 2.9-70.7%). Various shared pathophysiological pathways for these conditions, as well as proposed treatment strategies, were identified.Limitations: Heterogeneity of study design, populations, and methodology for identifying headache disorders and postural tachycardia syndrome limited the generalisability of results. Migraine is a commonly reported comorbidity in POTS, however the true prevalence cannot be determined from the current literature. Further studies are required to assess this comorbidity and investigate the underlying mechanisms, as well as identify effective treatment strategies.en
dc.language.isoeng-
dc.subjectMigraineen
dc.subjectPOTSen
dc.subjectpostural tachycardia syndromeen
dc.subjectprevalenceen
dc.subjectsystematic reviewen
dc.titleThe prevalence of headache disorders in Postural Tachycardia Syndrome: A systematic review and meta-analysis of the literature.en
dc.typeJournal Articleen
dc.identifier.journaltitleCephalalgia : An International Journal of Headacheen
dc.identifier.affiliationNeurologyen
dc.identifier.affiliationDepartment of Neurology, Alfred Hospital, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Neuroscience, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationHeadache and Facial Pain Group, University College London Queen Square Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdomen
dc.identifier.affiliationDepartment of Cardiology, Alfred Hospital, Melbourne Victoria, Australiaen
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/35469447/en
dc.identifier.doi10.1177/03331024221095153en
dc.type.contentTexten
dc.identifier.orcidhttps://orcid.org/0000-0003-4833-5507en
dc.identifier.orcidhttps://orcid.org/0000-0002-5438-6549en
dc.identifier.orcidhttps://orcid.org/0000-0002-4960-2294en
dc.identifier.pubmedid35469447-
local.name.researcherRay, Jason C
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
crisitem.author.deptNeurology-
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