Please use this identifier to cite or link to this item:
Title: Can insomnia be fatal? An Australian case of fatal familial insomnia.
Austin Authors: Habteslassie, Daniel;McMahon, Marcus A ;Wimaleswaran, Hari 
Affiliation: Respiratory and Sleep Medicine
Institute for Breathing and Sleep
Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia..
Issue Date: Apr-2022
Publication information: Internal Medicine Journal 2022; 52(4): 667-670
Abstract: Fatal familial insomnia (FFI) is a rare prion disease with autosomal dominant inheritance. Currently, there is only one published case study of FFI in Australia. FFI is universally fatal, with the disease duration ranging from 8 to 72 months. Clinically, it manifests with disordered sleep-wake cycle, dysautonomia, motor disturbances and neuropsychiatric disorders. We describe a case of FFI detailing the investigative process, including the importance of sleep assessment and polysomnography in obtaining a diagnosis.
DOI: 10.1111/imj.15737
ORCID: 0000-0003-3809-8691
Journal: Internal Medicine Journal
PubMed URL: 35419959
PubMed URL:
Type: Journal Article
Subjects: fatal familial insomnia
prion disease
sleep assessment
Appears in Collections:Journal articles

Show full item record

Page view(s)

checked on Sep 28, 2023

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.