Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/28862
Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Hamilton, Garry W | - |
dc.contributor.author | Yeoh, Julian | - |
dc.contributor.author | Dinh, Diem | - |
dc.contributor.author | Brennan, Angela | - |
dc.contributor.author | Yudi, Matias B | - |
dc.contributor.author | Freeman, Melanie | - |
dc.contributor.author | Horrigan, Mark | - |
dc.contributor.author | Martin, Lorelle | - |
dc.contributor.author | Reid, Christopher M | - |
dc.contributor.author | Yip, Thomas | - |
dc.contributor.author | Picardo, Sandra | - |
dc.contributor.author | Sharma, Anand | - |
dc.contributor.author | Duffy, Stephen J | - |
dc.contributor.author | Farouque, Omar | - |
dc.contributor.author | Clark, David J | - |
dc.contributor.author | Ajani, Andrew E | - |
dc.date | 2022 | - |
dc.date.accessioned | 2022-02-22T04:30:44Z | - |
dc.date.available | 2022-02-22T04:30:44Z | - |
dc.date.issued | 2022-01-31 | - |
dc.identifier.citation | Cardiovascular Revascularization Medicine : Including Molecular Interventions 2022; 41: 136-141 | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/28862 | - |
dc.description.abstract | Primary percutaneous coronary intervention (PCI) for patients with ST-elevation myocardial infarction (STEMI) is recommended within 90 min of first medical contact. Those without pre-hospital notification (PN) are less likely to meet reperfusion targets and are an understudied subset of the STEMI population. An observational cohort study from a multicentre PCI registry of consecutive patients undergoing primary PCI for STEMI between 2012 and 2017. Exclusion criteria included out-of-hospital cardiac arrest, prior thrombolysis, symptom onset >12 h prior, and cardiogenic shock. 2519 patients were included: 1392 (55.3%) without PN (no-PN group) and 1127 (44.7%) with PN (PN group). Those without PN had longer median DTBT (78 min vs 51 min, p < 0.001) and STBT (206 min vs 161 min, p < 0.001), with only 55% meeting DTBT targets out-of-hours in the no-PN group. No-PN patients had lower rates of AHA/ACC type B2/C lesions, GP IIb/IIIa use, aspiration thrombectomy and had smaller stent diameter (all p ≤ 0.003), suggesting smaller areas of ischemic myocardium. There were no significant differences in 30-day MACE (no-PN 5.6% vs PN 6.5%, p = 0.36) or long-term National Death Index linked mortality (no-PN 6.2% vs PN 7.9%, p = 0.09). Lack of PN did not independently predict long-term mortality. Despite comparably excellent outcomes overall, those without PN had longer ischemic times and were less likely to meet DTBT targets, especially after hours. Ischemic times may be a better evaluation of PN networks than hard clinical outcomes, and efficient systems of care tailored to the individual health service are essential to ensure timely reperfusion of patients with STEMI. | en |
dc.language.iso | eng | - |
dc.subject | Door-to-balloon time | en |
dc.subject | Ischemic time | en |
dc.subject | Outcomes | en |
dc.subject | Pre-hospital notification | en |
dc.subject | STEMI | en |
dc.title | Reperfusion times and outcomes in patients with ST-elevation myocardial infarction presenting without pre-hospital notification. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | Cardiovascular revascularization medicine : including molecular interventions | en |
dc.identifier.affiliation | Department of Cardiology, Box Hill Hospital, Melbourne, Australia.. | en |
dc.identifier.affiliation | Department of Cardiology, Ballarat Base Hospital, Ballarat, Australia.. | en |
dc.identifier.affiliation | Centre of Cardiovascular Research and Education in Therapeutics (CCRET), Monash University, Melbourne, Australia.. | en |
dc.identifier.affiliation | Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia.. | en |
dc.identifier.affiliation | Department of Medicine, University of Melbourne, Melbourne, Australia.. | en |
dc.identifier.affiliation | Department of Cardiology, Alfred Hospital, Melbourne, Australia.. | en |
dc.identifier.affiliation | School of Public Health, Curtin University, Perth, Western Australia, Australia.. | en |
dc.identifier.affiliation | Cardiology | en |
dc.identifier.affiliation | Department of Cardiology, University Hospital, Geelong, Australia.. | en |
dc.identifier.pubmeduri | https://pubmed.ncbi.nlm.nih.gov/35165049/ | en |
dc.identifier.doi | 10.1016/j.carrev.2022.01.024 | en |
dc.type.content | Text | en |
dc.identifier.orcid | 0000-0002-8900-7529 | en |
dc.identifier.orcid | 0000-0003-4957-186X | en |
dc.identifier.orcid | 0000-0002-3706-4150 | en |
dc.identifier.orcid | 0000-0002-5457-0856 | en |
dc.identifier.orcid | 0000-0003-2821-1451 | en |
dc.identifier.pubmedid | 35165049 | - |
local.name.researcher | Clark, David J | |
item.grantfulltext | none | - |
item.openairetype | Journal Article | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | University of Melbourne Clinical School | - |
Appears in Collections: | Journal articles |
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