Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/28117
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DC Field | Value | Language |
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dc.contributor.author | Bui, Dinh S | - |
dc.contributor.author | Perret, Jennifer L | - |
dc.contributor.author | Walters, E Haydn | - |
dc.contributor.author | Abramson, Michael J | - |
dc.contributor.author | Burgess, John A | - |
dc.contributor.author | Bui, Minh Q | - |
dc.contributor.author | Bowatte, Gayan | - |
dc.contributor.author | Lowe, Adrian J | - |
dc.contributor.author | Russell, Melissa A | - |
dc.contributor.author | Alif, Sheikh M | - |
dc.contributor.author | Thompson, Bruce R | - |
dc.contributor.author | Hamilton, Garun S | - |
dc.contributor.author | Giles, Graham G | - |
dc.contributor.author | Thomas, Paul S | - |
dc.contributor.author | Morrison, Stephen | - |
dc.contributor.author | Johns, David P | - |
dc.contributor.author | Knibbs, Luke D | - |
dc.contributor.author | Zock, Jan-Paul | - |
dc.contributor.author | Marcon, Alessandro | - |
dc.contributor.author | Garcia-Aymerich, Judith | - |
dc.contributor.author | Erbas, Bircan | - |
dc.contributor.author | Jarvis, Deborah | - |
dc.contributor.author | Svanes, Cecilie | - |
dc.contributor.author | Lodge, Caroline J | - |
dc.contributor.author | Dharmage, Shyamali C | - |
dc.date.accessioned | 2021-11-24T05:40:04Z | - |
dc.date.available | 2021-11-24T05:40:04Z | - |
dc.date.issued | 2020-03 | - |
dc.identifier.citation | Annals of the American Thoracic Society 2020; 17(3): 302-312. | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/28117 | - |
dc.description.abstract | Rationale: Interactions between early life and adult insults on lung function decline are not well understood, with most studies investigating prebronchodilator (pre-BD) FEV1 decline.Objectives: To investigate relationships between adult risk factors and pre- and post-BD lung function decline and their potential effect modification by early life and genetic factors.Methods: Multiple regression was used to examine associations between adult exposures (asthma, smoking, occupational exposures, traffic pollution, and obesity) and decline in both pre- and post-BD spirometry (forced expiratory volume in 1 s [FEV1], forced vital capacity [FVC], and FEV1/FVC) between ages 45 and 53 years in the Tasmanian Longitudinal Health Study (n = 857). Effect modification of these relationships by childhood respiratory risk factors, including low childhood lung function and GST (glutathione S-transferase) gene polymorphisms, was investigated.Results: Baseline asthma, smoking, occupational exposure to vapors/gases/dusts/fumes, and living close to traffic were associated with accelerated decline in both pre- and post-BD FEV1. These factors were also associated with FEV1/FVC decline. Occupational exposure to aromatic solvents was associated with pre-BD but not post-BD FEV1 decline. Maternal smoking accentuated the effect of personal smoking on pre- and post-BD FEV1 decline. Lower childhood lung function and having the GSTM1 null allele accentuated the effect of occupational exposure to vapors/gases/dusts/fumes and personal smoking on post-BD FEV1 decline. Incident obesity was associated with accelerated decline in FEV1 and more pronounced in FVC.Conclusions: This study provides new evidence for accentuation of individual susceptibility to adult risk factors by low childhood lung function, GSTM1 genotype, and maternal smoking. | en |
dc.language.iso | eng | |
dc.subject | bronchodilator | en |
dc.subject | decline | en |
dc.subject | interaction | en |
dc.subject | lung function | en |
dc.subject | susceptibility | en |
dc.title | Lifetime Risk Factors for Pre- and Post-Bronchodilator Lung Function Decline. A Population-based Study. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | Annals of the American Thoracic Society | en |
dc.identifier.affiliation | Institute for Breathing and Sleep.. | en |
dc.identifier.affiliation | University of Queensland, Brisbane, Queensland, Australia.. | en |
dc.identifier.affiliation | Department of Respiratory Medicine, School of Medicine, Flinders University, Adelaide, South Australia, Australia.. | en |
dc.identifier.affiliation | School of Public Health, the University of Queensland, Brisbane, Queensland, Australia.. | en |
dc.identifier.affiliation | School of Psychology and Public Health, La Trobe University, Melbourne, Victoria, Australia.. | en |
dc.identifier.affiliation | Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College London, London, United Kingdom.. | en |
dc.identifier.affiliation | Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.. | en |
dc.identifier.affiliation | Allergy and Lung Health Unit, The University of Melbourne, Melbourne, Victoria, Australia.. | en |
dc.identifier.affiliation | Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health.. | en |
dc.identifier.affiliation | Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.. | en |
dc.identifier.affiliation | Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway.. | en |
dc.identifier.affiliation | Department of Analytical Chemistry and Toxicology, Hanoi University of Pharmacy, Hanoi, Vietnam.. | en |
dc.identifier.affiliation | School of Clinical Sciences, Monash Health, Melbourne, Victoria, Australia.. | en |
dc.identifier.affiliation | Monash Lung and Sleep, Monash Health, Melbourne, Victoria, Australia.. | en |
dc.identifier.affiliation | Precision Medicine, School of Clinical Sciences at Monash Health, Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.. | en |
dc.identifier.affiliation | Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.. | en |
dc.identifier.affiliation | Prince of Wales Hospital Clinical School and School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia.. | en |
dc.identifier.affiliation | ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.. | en |
dc.identifier.affiliation | Universitat Pompeu Fabra (UPF), Barcelona, Spain.. | en |
dc.identifier.affiliation | Central Clinical School, Monash University, Melbourne, Victoria, Australia.. | en |
dc.identifier.affiliation | Allergy, Immunology, and Respiratory Medicine, The Alfred Hospital, Melbourne, Victoria, Australia.. | en |
dc.identifier.affiliation | School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia... | en |
dc.identifier.affiliation | CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.. | en |
dc.identifier.pubmeduri | https://pubmed.ncbi.nlm.nih.gov/31800292/ | en |
dc.identifier.doi | 10.1513/AnnalsATS.201904-329OC | en |
dc.type.content | Text | en |
dc.identifier.orcid | 0000-0002-4388-784X | en |
dc.identifier.orcid | 0000-0002-7097-4586 | en |
dc.identifier.orcid | 0000-0001-6063-1937 | en |
dc.identifier.orcid | 0000-0001-7034-0615 | en |
dc.identifier.pubmedid | 31800292 | |
local.name.researcher | Perret, Jennifer L | |
item.languageiso639-1 | en | - |
item.openairetype | Journal Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Institute for Breathing and Sleep | - |
Appears in Collections: | Journal articles |
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