Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/28105
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dc.contributor.authorRaab, Anja M-
dc.contributor.authorBrinkhof, Martin W G-
dc.contributor.authorBerlowitz, David J-
dc.contributor.authorPostma, Karin-
dc.contributor.authorGobets, David-
dc.contributor.authorHirschfeld, Sven-
dc.contributor.authorHopman, Maria T E-
dc.contributor.authorHuber, Burkhart-
dc.contributor.authorHund-Georgiadis, Margret-
dc.contributor.authorJordan, Xavier-
dc.contributor.authorSchubert, Martin-
dc.contributor.authorWildburger, Renate-
dc.contributor.authorMueller, Gabi-
dc.date2020-
dc.date.accessioned2021-11-24T05:39:56Z-
dc.date.available2021-11-24T05:39:56Z-
dc.date.issued2020-11-05-
dc.identifier.citationBMJ open 2020; 10(11): e038204en
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/28105-
dc.description.abstractPneumonia is one of the leading complications and causes of death after a spinal cord injury (SCI). After a cervical or thoracic lesion, impairment of the respiratory muscles decreases respiratory function, which increases the risk of respiratory complications. Pneumonia substantially reduces patient's quality of life, may prolong inpatient rehabilitation time, increase healthcare costs or at worse, lead to early death. Respiratory function and coughing can be improved through various interventions after SCI, but the available evidence as to which aspect of respiratory care should be optimised is inconclusive. Furthermore, ability of respiratory function parameters to predict pneumonia risk is insufficiently established. This paper details the protocol for a large-scale, multicentre research project that aims to evaluate the ability of parameters of respiratory function to predict and understand variation in inpatient risk of pneumonia in SCI. RESCOM, a prospective cohort study, began recruitment in October 2016 across 10 SCI rehabilitation centres from Australia, Austria, Germany, the Netherlands and Switzerland. Inpatients with acute SCI, with complete or incomplete cervical or thoracic lesions, 18 years or older and not/no more dependent on 24-hour mechanical ventilation within the first 3 months after injury are eligible for inclusion. The target sample size is 500 participants. The primary outcome is an occurrence of pneumonia; secondary outcomes include pneumonia-related mortality and quality of life. We will use the longitudinal data for prognostic models on inpatient pneumonia risk factors. The study has been reviewed and approved by all local ethics committees of all participating centres. Study results will be disseminated to the scientific community through peer-reviewed journals and conference presentations, to the SCI community, other stakeholders and via social media, newsletters and engagement activities. ClinicalTrials.gov NCT02891096.en
dc.language.isoeng
dc.subjectepidemiologyen
dc.subjectrehabilitation medicineen
dc.subjectrespiratory infectionsen
dc.titleRespiratory function and respiratory complications in spinal cord injury: protocol for a prospective, multicentre cohort study in high-income countries.en
dc.typeJournal Articleen
dc.identifier.journaltitleBMJ openen
dc.identifier.affiliationInstitute for Breathing and Sleepen
dc.identifier.affiliationClinical Trial Unit, Swiss Paraplegic Center, Nottwil, Switzerlanden
dc.identifier.affiliationDepartment of Physiotherapy, University of Melbourne, Melbourne, Victoria, Australiaen
dc.identifier.affiliationLife Course Epidemiology Group, Swiss Paraplegic Research, Nottwil, Switzerlanden
dc.identifier.affiliationDepartment of Rehabilitation Medicine, Rijndam Rehabilitation and Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlandsen
dc.identifier.affiliationDepartment of Rehabilitation Medicine, Heliomare Rehabilitation Center, Wijk aan Zee, The Netherlandsen
dc.identifier.affiliationCenter for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlandsen
dc.identifier.affiliationTrauma Surgery, AUVA Rehabilitation Center Häring, Bad Häring, Austriaen
dc.identifier.affiliationClinic for neurorehabilitation and paraplegiology, REHAB Basel, Basel, Switzerlanden
dc.identifier.affiliationSpinal Cord Unit, Clinique romande de réadaptation, Sion, Switzerlanden
dc.identifier.affiliationSpinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerlanden
dc.identifier.affiliationAllgemeine Unfallversicherungsanstalt, AUVA Rehabilitation Clinic Tobelbad, Tobelbad, Austriaen
dc.identifier.affiliationClinical Trial Unit, Swiss Paraplegic Center, Nottwil, Switzerlanden
dc.identifier.affiliationDepartment of Spinal Cord Medicine, BG Trauma Hospital, Hamburg, Germanyen
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/33154049/en
dc.identifier.doi10.1136/bmjopen-2020-038204en
dc.type.contentTexten
dc.identifier.orcid0000-0002-4139-2173en
dc.identifier.orcid0000-0002-9319-665Xen
dc.identifier.orcid0000-0003-2543-8722en
dc.identifier.orcid0000-0002-0729-6778en
dc.identifier.orcid0000-0003-0270-5672en
dc.identifier.orcid0000-0001-9504-5452en
dc.identifier.orcid0000-0002-4415-2888en
dc.identifier.orcid0000-0003-3389-0057en
dc.identifier.orcid0000-0001-9820-3823en
dc.identifier.orcid0000-0001-6391-3737en
dc.identifier.pubmedid33154049
local.name.researcherBerlowitz, David J
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptPhysiotherapy-
crisitem.author.deptInstitute for Breathing and Sleep-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
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