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DC Field | Value | Language |
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dc.contributor.author | Copaescu, Ana | - |
dc.contributor.author | Phillips, Elizabeth J | - |
dc.contributor.author | Trubiano, Jason | - |
dc.date | 2021 | - |
dc.date.accessioned | 2021-11-03T00:35:01Z | - |
dc.date.available | 2021-11-03T00:35:01Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Current opinion in infectious diseases 2021; 34(6): 559-572 | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/27856 | - |
dc.description.abstract | The goal of this article is to provide an updated understanding and evidence-based approach where possible for antifungal hypersensitivity. This includes recognition of clinical phenotype, implications for cross-reactivity and diagnostic, and management strategy for immediate and delayed hypersensitivity reactions. Antifungal hypersensitivity reactions can be classified according to their latency (immediate or delayed) and clinical phenotype. The majority of the cases described in the literature are delayed T-cell mediated reactions of various severities but immediate reactions consistent with non-Immunoglobulin E (IgE)-mediated mast cell activation and IgE-mediated reactions have also been described. Ancillary information such as skin testing, drug challenge and ex vivo experimental approaches can aid causality assessments and inform antifungal class cross-reactivity, which help optimize antifungal prescribing and stewardship. This review will update the clinician on mechanisms of drug hypersensitivity as well as providing a structured approach to the recognition, diagnosis and management of antifungal hypersensitivity reaction. | en |
dc.language.iso | eng | - |
dc.title | Antifungal hypersensitivity reactions and cross-reactivity patterns. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | Current Opinion in Infectious Diseases | en |
dc.identifier.affiliation | Department of Medicine, Division of Allergy and Clinical Immunology, McGill University Health Centre (MUHC) The Research Institute of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada | en |
dc.identifier.affiliation | Centre for Antibiotic Allergy and Research | en |
dc.identifier.affiliation | Infectious Diseases | en |
dc.identifier.affiliation | Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia | en |
dc.identifier.affiliation | Department of Infectious Diseases, Vanderbilt University Medical Centre, Nashville, Tennessee, USA | en |
dc.identifier.affiliation | Department of Oncology, Sir Peter MacCallum Cancer Centre, The University of Melbourne, Parkville | en |
dc.identifier.affiliation | Medicine (University of Melbourne) | en |
dc.identifier.affiliation | The National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Parkville, Victoria, Australia | en |
dc.identifier.doi | 10.1097/QCO.0000000000000786 | en |
dc.type.content | Text | en |
dc.identifier.pubmedid | 34693920 | - |
local.name.researcher | Copaescu, Ana | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
crisitem.author.dept | Infectious Diseases | - |
crisitem.author.dept | Infectious Diseases | - |
crisitem.author.dept | Medicine (University of Melbourne) | - |
crisitem.author.dept | Centre for Antibiotic Allergy and Research | - |
Appears in Collections: | Journal articles |
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