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dc.contributor.authorBensley, Jonathan G-
dc.contributor.authorDhillon, Haryana M-
dc.contributor.authorEvans, Sue M-
dc.contributor.authorEvans, Melanie-
dc.contributor.authorBolton, Damien M-
dc.contributor.authorDavis, Ian D-
dc.contributor.authorDodds, Lachlan-
dc.contributor.authorFrydenberg, Mark-
dc.contributor.authorKearns, Paul-
dc.contributor.authorLawrentschuk, Nathan-
dc.contributor.authorMurphy, Declan G-
dc.contributor.authorMillar, Jeremy L-
dc.contributor.authorPapa, Nathan-
dc.identifier.citationPsycho-oncology 2022; 31(3): 496-503en
dc.description.abstractFeeling depressed and lethargic are common side effects of prostate cancer (PCa) and its treatments. We examined the incidence and severity of feeling depressed and lack of energy in patients in a population based PCa registry. We included men diagnosed with PCa between 2015 and 2019 in Victoria, Australia, and enrolled in the Prostate Cancer Outcomes Registry. The primary outcome measures were responses to two questions on the Expanded Prostate Cancer Index Composite (EPIC-26) patient reported instrument: problems with feeling depressed and problems with lack of energy 12 months following treatment. We evaluated associations between these and age, cancer risk category, treatment type, and urinary, bowel, and sexual function. Both outcome questions were answered by 9712 out of 12,628 (77%) men. 981 patients (10%) reported at least moderate problems with feeling depressed; 1563 (16%) had at least moderate problems with lack of energy and 586 (6.0%) with both. Younger men reported feeling depressed more frequently than older men. Lack of energy was more common for treatments that included androgen deprivation therapy than not (moderate/big problems: 31% vs. 13%), irrespective of disease risk category. Both outcomes were associated with poorer urinary, bowel, and sexual functional domain scores. Self-reported depressive feelings and lack of energy were frequent in this population-based registry. Problems with feeling depressed were more common in younger men and lack of energy more common in men having hormonal treatment. Clinicians should be aware of the incidence of these symptoms in these at-risk groups and be able to screen for them.en
dc.subjectandrogen deprivationen
dc.subjectprostate canceren
dc.titleSelf-reported lack of energy or feeling depressed 12 months after treatment in men diagnosed with prostate cancer within a population-based registry.en
dc.typeJournal Articleen
dc.identifier.affiliationMedical Oncology Unit, Eastern Health, Melbourne, Victoria, Australiaen
dc.identifier.affiliationOlivia Newton-John Cancer Wellness and Research Centreen
dc.identifier.affiliationBallarat Health Services, Ballarat, Victoria, Australiaen
dc.identifier.affiliationDepartment of Surgery, Cabrini Institute, Cabrini Health, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationBarwon Health, Geelong, Victoria, Australiaen
dc.identifier.affiliationSir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDivision of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australiaen
dc.identifier.affiliationEJ Whitten Prostate Cancer Research Centre, Epworth Healthcare, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Surgery and Department of Urology, University of Melbourne at Royal Melbourne Hospital, Melbourne, Victoria, Australiaen
dc.identifier.affiliationEastern Health Clinical School, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationCentral Clinical School, Monash University, The Alfred Centre, Melbourne, Victoria, Australiaen
dc.identifier.affiliationRadiation Oncology, Alfred Health, Melbourne, Victoria, Australiaen
dc.identifier.affiliationPsycho-Oncology Cooperative Research Group, School of Psychology, Faculty of Science, The University of Sydney, Sydney, New South Wales, Australiaen
dc.identifier.affiliationVictorian Cancer Registry, Cancer Council Victoria, Melbourne, Victoria, Australiaen
dc.identifier.affiliationCentre for Medical Psychology and Evidence-Based Decision-Making, School of Psychology, Faculty of Science, The University of Sydney, Sydney, New South Wales, Australiaen
dc.identifier.affiliationSurgery (University of Melbourne)en
dc.identifier.pubmedid34623735-, Damien M
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
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