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dc.contributor.authorZhao, Fei-Yi-
dc.contributor.authorFu, Qiang-Qiang-
dc.contributor.authorKennedy, Gerard A-
dc.contributor.authorConduit, Russell-
dc.contributor.authorWu, Wen-Zhong-
dc.contributor.authorZhang, Wen-Jing-
dc.contributor.authorZheng, Zhen-
dc.identifier.citationEvidence-Based Complementary and Alternative Medicine : eCAM 2021; 2021: 5566742en
dc.description.abstractMany women with perimenopausal insomnia (PMI) have sought alternative therapies such as acupuncture because of concerns about risks associated with hormone replacement therapy (HRT) and/or psychotropic drugs. This systematic review aimed to clarify if acupuncture alone or combined with standard Western pharmacotherapy (HRT and/or psychotropic drugs) is more effective in ameliorating PMI in comparison to pharmacotherapy alone. Randomized controlled trials (RCTs) of PMI treatment via acupuncture alone or combined with Western pharmacotherapy versus Western pharmacotherapy were searched for from eleven databases from inception to March 2020. Cochrane criteria were followed. Fifteen studies involving 1410 women were analyzed. Meta-analysis indicated that acupuncture significantly reduced the global scores of Pittsburgh Sleep Quality Index (PSQI) [MD = -2.38, 95% CI (-3.38, -1.37), p < 0.01] and Kupperman Index [MD = -5.95, 95% CI (-10.68, -1.21), p = 0.01], compared with hypnotics. Acupuncture combined with hypnotics was more effective than hypnotics alone in decreasing PSQI scores [MD = -3.13, 95% CI (-5.43, -0.83), p < 0.01]. Too few RCTs were available to investigate the clinical efficacy differences between acupuncture and HRT/psychotropic drugs other than hypnotics. Despite limited evidence, in comparison to hypnotics, acupuncture was associated with significant improvements in PMI, and reductions of other menopausal symptoms. This finding suggests that acupuncture may be a useful addition to treatment for PMI.en
dc.titleComparative Utility of Acupuncture and Western Medication in the Management of Perimenopausal Insomnia: A Systematic Review and Meta-Analysis.en
dc.typeJournal Articleen
dc.identifier.journaltitleEvidence-Based Complementary and Alternative Medicine : eCAMen
dc.identifier.affiliationJiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, Chinaen
dc.identifier.affiliationYangpu Hospital, Tongji University School of Medicine, Shanghai, Chinaen
dc.identifier.affiliationSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australiaen
dc.identifier.affiliationSchool of Science, Psychology and Sport, Federation University, Mount Helen, Victoria, Australiaen
dc.identifier.affiliationInstitute for Breathing and Sleepen
dc.identifier.affiliationShanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, Chinaen
dc.identifier.affiliationDepartment of Nursing, School of International Medical Technology, Shanghai Sanda University, Shanghai 201209, Chinaen
dc.identifier.pubmedid33986818, Gerard A
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.grantfulltextnone- and Sleep Medicine- for Breathing and Sleep-
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