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dc.contributor.authorCori, Jennifer M-
dc.contributor.authorTurner, Sophie-
dc.contributor.authorWestlake, Justine-
dc.contributor.authorNaqvi, Aqsa-
dc.contributor.authorFtouni, Suzanne-
dc.contributor.authorWilkinson, Vanessa E-
dc.contributor.authorVakulin, Andrew-
dc.contributor.authorO'Donoghue, Fergal J-
dc.contributor.authorHoward, Mark E-
dc.identifier.citationSleep health 2021; 7(5): 644-651en
dc.description.abstractTo determine whether continuous eye blink measures could identify drowsiness in patients with obstructive sleep apnea (OSA) during a week of naturalistic driving. Observational study comparing OSA patients and healthy controls. Regular naturalistic driving across one week. Fifteen untreated moderate to severe OSA patients and 15 age (± 5 years) and sex (female = 6) matched healthy controls. Participants wore an eye blink drowsiness recording device during their regular driving for one week. During regular driving, the duration of time with no ocular movements (quiescence), was elevated in the OSA group by 43% relative to the control group (mean [95% CI] 0.20[0.17, 0.25] vs 0.14[0.12, 0.18] secs, P = .011). During long drives only, the Johns Drowsiness Scale was also elevated and increased by 62% in the OSA group relative to the control group (1.05 [0.76, 1.33] vs 0.65 [0.36, 0.93], P = .0495). Across all drives, critical drowsiness events (defined by a Johns Drowsiness Scale score ≥2.6) were twice as frequent in the OSA group than the control group (rate ratio [95% CI] =1.93 [1.65, 2.25], P ≤ .001). OSA patients were drowsier than healthy controls according to some of the continuous real time eye blink drowsiness measures. The findings of this pilot study suggest that there is potential for eye blink measures to be utilized to assess fitness to drive in OSA patients. Future work should assess larger samples, as well as the relationship of eye blink measures to conventional fitness to drive assessments and crash risk.en
dc.subjectSleep disordered breathingen
dc.titleEye blink parameters to indicate drowsiness during naturalistic driving in participants with obstructive sleep apnea: A pilot study.en
dc.typeJournal Articleen
dc.identifier.journaltitleSleep Healthen
dc.identifier.affiliationCircadian Therapeutics, Oxford, UKen
dc.identifier.affiliationSleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UKen
dc.identifier.affiliationDepartment of Medicine, The University of Melbourne, Parkville, Victoria, Australiaen
dc.identifier.affiliationSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australiaen
dc.identifier.affiliationInstitute for Breathing and Sleepen
dc.identifier.affiliationRespiratory and Sleep Medicineen
dc.identifier.affiliationAdelaide Institute for Sleep Health, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australiaen
dc.identifier.affiliationNeuroSleep-NHMRC Centre of Research Excellence, Woolcock Institute of Medical Research, University of Sydney, Sydney, New South Wales, Australiaen
dc.identifier.pubmedid33935013-, Jennifer M
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.cerifentitytypePublications- for Breathing and Sleep- for Breathing and Sleep- and Sleep Medicine- for Breathing and Sleep- for Breathing and Sleep-
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