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dc.contributor.authorZendeli, Afrodite-
dc.contributor.authorBui, Minh-
dc.contributor.authorFischer, Lukas-
dc.contributor.authorGhasem-Zadeh, Ali-
dc.contributor.authorSchima, Wolfgang-
dc.contributor.authorSeeman, Ego-
dc.identifier.citationJournal of Clinical Medicine 2021; 10(5): 1123en
dc.description.abstractTo determine whether stress fractures are associated with bone microstructural deterioration we quantified distal radial and the unfractured distal tibia using high resolution peripheral quantitative computed tomography in 26 cases with lower limb stress fractures (15 males, 11 females; mean age 37.1 ± 3.1 years) and 62 age-matched healthy controls (24 males, 38 females; mean age 35.0 ± 1.6 years). Relative to controls, in men, at the distal radius, cases had smaller cortical cross sectional area (CSA) (p = 0.012), higher porosity of the outer transitional zone (OTZ) (p = 0.006), inner transitional zone (ITZ) (p = 0.043) and the compact-appearing cortex (CC) (p = 0.023) while trabecular vBMD was lower (p = 0.002). At the distal tibia, cases also had a smaller cortical CSA (p = 0.008). Cortical porosity was not higher, but trabecular vBMD was lower (p = 0.001). Relative to controls, in women, cases had higher distal radial porosity of the OTZ (p = 0.028), ITZ (p = 0.030) not CC (p = 0.054). Trabecular vBMD was lower (p = 0.041). Distal tibial porosity was higher in the OTZ (p = 0.035), ITZ (p = 0.009), not CC. Stress fractures are associated with compromised cortical and trabecular microstructure.en
dc.subjectbone microstructural deteriorationen
dc.subjectcortical porosityen
dc.subjecthigh resolution peripheral quantitative computed tomographyen
dc.subjectstress fractureen
dc.titleHigh Cortico-Trabecular Transitional Zone Porosity and Reduced Trabecular Density in Men and Women with Stress Fractures.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of Clinical Medicineen
dc.identifier.affiliationMedical Department of Internal Medicine, Rheumatology and Endocrinology at Krankenhaus Herz Jesu, 1030 Vienna, Austriaen
dc.identifier.affiliationMedicine (University of Melbourne)en
dc.identifier.affiliationCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne 3000, Australiaen
dc.identifier.affiliationComputational Imaging Research Lab, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, 1090 Vienna, Austriaen
dc.identifier.affiliationSoftware Competence Center Hagenberg GmbH (SCCH), 4232 Hagenberg, Austriaen
dc.identifier.affiliationDepartment of Diagnostic and Interventional Radiology-Barmherzige Schwestern Krankenhaus, Goettlicher Heiland Krankenhaus und Sankt Josef Krankenhaus, 1060 Vienna, Austriaen
dc.identifier.pubmedid33800284, Ali
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
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