Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/26074
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dc.contributor.authorKry, Stephen F-
dc.contributor.authorLye, Jessica-
dc.contributor.authorClark, Catharine H-
dc.contributor.authorAndratschke, Nicolaus-
dc.contributor.authorDimitriadis, Alexis-
dc.contributor.authorFollowill, David-
dc.contributor.authorHowell, Rebecca-
dc.contributor.authorHussein, Mohammad-
dc.contributor.authorIshikawa, Masayori-
dc.contributor.authorKito, Satoshi-
dc.contributor.authorKron, Tomas-
dc.contributor.authorLee, Jonny-
dc.contributor.authorMichalski, Jeff-
dc.contributor.authorFilippo Monti, Angelo-
dc.contributor.authorReynaert, Nick-
dc.contributor.authorTaylor, Paige-
dc.contributor.authorVenables, Karen-
dc.contributor.authorXiao, Ying-
dc.contributor.authorLehmann, Joerg-
dc.date2021-03-16-
dc.date.accessioned2021-03-24T21:38:48Z-
dc.date.available2021-03-24T21:38:48Z-
dc.date.issued2021-06-
dc.identifier.citationRadiotherapy and Oncology 2021; 159: 106-111en_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/26074-
dc.description.abstractTo promote consistency in clinical trials by recommending a uniform framework as it relates to radiation transport and dose calculation in water versus in medium. The Global Quality Assurance of Radiation Therapy Clinical Trials Harmonisation Group (GHG; www.rtqaharmonization.org) compared the differences between dose to water in water (Dw,w), dose to water in medium (Dw,m), and dose to medium in medium (Dm,m). This was done based on a review of historical frameworks, existing literature and standards, clinical issues in the context of clinical trials, and the trajectory of radiation dose calculations. Based on these factors, recommendations were developed. No framework was found to be ideal or perfect given the history, complexity, and current status of radiation therapy. Nevertheless, based on the evidence available, the GHG established a recommendation preferring dose to medium in medium (Dm,m). Dose to medium in medium (Dm,m) is the preferred dose calculation and reporting framework. If an institution's planning system can only calculate dose to water in water (Dw,w), this is acceptable.en_US
dc.language.isoeng-
dc.subjectClinical trialen_US
dc.subjectDose calculationen_US
dc.subjectDose mediumen_US
dc.subjectGHGen_US
dc.subjectRadiation dosageen_US
dc.titleReport dose-to-medium in clinical trials where available; a consensus from the global Harmonisation group to maximize consistency.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleRadiotherapy and Oncologyen_US
dc.identifier.affiliationImaging and Radiation Oncology Core, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.en_US
dc.identifier.affiliationEuropean Organisation for Research and Treatment of Cancer (EORTC), Department of Medical Physics, ASST GOM Niguarda Hospital, Milan, Italyen_US
dc.identifier.affiliationAustralian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, Melbourne, Australiaen_US
dc.identifier.affiliationOlivia Newton-John Cancer Wellness and Research Centreen_US
dc.identifier.affiliationTrans Tasman Radiation Oncology Group (TROG), Newcastle, NSW, Australiaen_US
dc.identifier.affiliationPeter MacCallum Cancer Centre, Melbourne, VIC, Australiaen_US
dc.identifier.affiliationRadiation Oncology Department, Calvary Mater Newcastle, Newcastle, NSW, Australiaen_US
dc.identifier.affiliationSchool of Mathematical and Physical Sciences, University of Newcastle, Newcastle, NSW, Australiaen_US
dc.identifier.affiliationInstitute of Medical Physics, University of Sydney, Sydney, NSW, Australiaen_US
dc.identifier.affiliationNIHR Radiotherapy Trials Quality Assurance Group, University College London Hospital, University College London, National Physical Laboratory United Kingdomen_US
dc.identifier.affiliationEuropean Organisation for Research and Treatment of Cancer Radiotherapy Quality Assurance Group, University Hospital of Zurich, University of Zurich, Zurich, Switzerlanden_US
dc.identifier.affiliationDosimetry and Medical Radiation Physics Section, Division of Human Health, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Vienna, Austriaen_US
dc.identifier.affiliationImaging and Radiation Oncology Core, The University of Texas MD Anderson Cancer Center, Houston, TX, United Statesen_US
dc.identifier.affiliationRadiation Dosimetry Services, The University of Texas MD Anderson Cancer Center, Houston TX, United Statesen_US
dc.identifier.affiliationNational Physical Laboratory United Kingdomen_US
dc.identifier.affiliationJapan Clinical Oncology Group, Faculty of Health Sciences, Hokkaido University, Japanen_US
dc.identifier.affiliationJapan Clinical Oncology Group, Department of Radiation Oncology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospitalen_US
dc.identifier.affiliationNIHR Radiotherapy Trials Quality Assurance Group, Mount Vernon Cancer Centre, Northwood, United Kingdomen_US
dc.identifier.affiliationImaging and Radiation Oncology Core, Washington University School of Medicine, St. Louis, MO, United Statesen_US
dc.identifier.affiliationEuropean Organisation for Research and Treatment of Cancer, Medical Physics Department, Jules Bordet Institute, Université Libre de Bruxelles, Brussels, Belgiumen_US
dc.identifier.affiliationImaging and Radiation Oncology Core, The University of Texas MD Anderson Cancer Center, Houston, TX, United Statesen_US
dc.identifier.affiliationNIHR Radiotherapy Trials Quality Assurance Group, Mount Vernon Cancer Centre, Northwood, United Kingdomen_US
dc.identifier.affiliationImaging and Radiation Oncology Core, University of Pennsylvania, Philadelphia, PA, United Statesen_US
dc.identifier.doi10.1016/j.radonc.2021.03.006en_US
dc.type.contentTexten_US
dc.identifier.pubmedid33741471-
local.name.researcherLye, Jessica
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
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