Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/25665
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dc.contributor.authorLim Joon, Daryl-
dc.contributor.authorChao, Michael-
dc.contributor.authorPiccolo, Angelina-
dc.contributor.authorSchneider, Michal-
dc.contributor.authorAnderson, Nigel-
dc.contributor.authorHandley, Monica-
dc.contributor.authorBenci, Margaret-
dc.contributor.authorOng, Wee Loon-
dc.contributor.authorDaly, Karen-
dc.contributor.authorMorrell, Rebecca-
dc.contributor.authorWan, Kenneth-
dc.contributor.authorLawrentschuk, Nathan-
dc.contributor.authorForoudi, Farshad-
dc.contributor.authorJenkins, Trish-
dc.contributor.authorAngus, David-
dc.contributor.authorWada, Morikatsu-
dc.contributor.authorSengupta, Shomik-
dc.contributor.authorKhoo, Vincent-
dc.date2021-01-12-
dc.date.accessioned2021-01-15T04:59:51Z-
dc.date.available2021-01-15T04:59:51Z-
dc.date.issued2021-09-
dc.identifier.citationJournal of Medical Radiation Sciences 2021; 68(3): 289-297en
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/25665-
dc.description.abstractGuidelines recommend that the proximal seminal vesicles (PrSV) should be included in the clinical target volume for locally advanced prostate cancer patients undergoing radiotherapy. Verification and margins for the prostate may not necessarily account for PrSV displacement. The purpose was to determine the inter-fraction displacement of the PrSV relative to the prostate during radiotherapy. Fiducials were inserted into the prostate, and right and left PrSV (RSV and LSV) in 30 prostate cancer patients. Correctional shifts for the prostate, right and left PrSV and pelvic bones were determined from each patient's 39 daily orthogonal portal images relative to reference digitally reconstructed radiographs. There was a significant displacement of the RSV relative to the prostate in all directions: on average 0.38 mm (95% confidence interval (CI) 0.26 to 0.50) to the left, 0.80-0.81 mm (CI 0.68 to 0.93) superiorly and 1.51 mm (CI 1.36 to 1.65) posteriorly. The LSV was significantly displaced superiorly to the prostate 1.09-1.13 mm (CI 0.97 to 1.25) and posteriorly 1.81 mm (CI 1.67 to 1.96), but not laterally (mean 0.06, CI -0.06 to 0.18). The calculated PTV margins (left-right, superior-inferior, posterior-anterior) were 4.9, 5.3-5.6 and 4.8 mm for the prostate, 5.2, 7.1-8.0 and 9.7 mm for the RSV, and 7.2, 7.5-7.6 and 8.6 mm for the LSV. There is a significant displacement of the PrSV relative to the prostate during radiotherapy. Greater margins are recommended for the PrSV compared to the prostate.en
dc.language.isoeng-
dc.subjectClinical target volumeen
dc.subjectdisplacementen
dc.subjectfiducial markersen
dc.subjectmarginsen
dc.subjectplanning target volumeen
dc.subjectProstate canceren
dc.subjectradiotherapyen
dc.subjectradiotherapy planningen
dc.subjectseminal vesiclesen
dc.titleProximal seminal vesicle displacement and margins for prostate cancer radiotherapy.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of Medical Radiation Sciencesen
dc.identifier.affiliationOlivia Newton-John Cancer Wellness and Research Centreen
dc.identifier.affiliationMonash University, Melbourne, Vic., Australiaen
dc.identifier.affiliationRadiation Oncologyen
dc.identifier.affiliationUrologyen
dc.identifier.affiliationRoyal Marsden NHS Foundation Trust, London, UKen
dc.identifier.doi10.1002/jmrs.457en
dc.type.contentTexten
dc.identifier.orcid0000-0002-1947-9694en
dc.identifier.orcid0000-0002-5521-3455en
dc.identifier.orcid0000-0002-4826-2339en
dc.identifier.orcid0000-0001-6657-7193en
dc.identifier.orcid0000-0001-8387-0965en
dc.identifier.pubmedid33432719-
local.name.researcherAngus, David
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptUrology-
crisitem.author.deptSurgery-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptUrology-
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