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dc.contributor.authorNaorungroj, Thummaporn-
dc.contributor.authorSerpa Neto, Ary-
dc.contributor.authorYanase, Fumitaka-
dc.contributor.authorBittar, Intissar-
dc.contributor.authorEastwood, Glenn M-
dc.contributor.authorBellomo, Rinaldo-
dc.identifier.citationBlood purification 2020; online first: 8 Decemberen
dc.description.abstractThe acute kidney injury (AKI) risk score helps detect moderate and severe AKI in the next 12-24 h. However, inappropriate urine collection may impact its results. The aim of this study was to evaluate the stability of NephroCheck® after urine storage at different temperatures. The urine sample was centrifuged and split into 3 tubes. One was tested as soon as possible by the laboratory. The other 2 samples were frozen at -20 and -80°C, and the NephroCheck® test was performed 8 weeks later. The mean values of the AKI risk score were 1.19 ± 0.93, 1.15 ± 1.14, and 1.20 ± 1.11 (ng/mL)2/1,000 for fresh urine, -20, and -80°C, respectively (p = 0.70). Spearman's rank correlation for -20 and -80°C versus immediate processing was strong with a rho of 0.82 and 0.98, respectively. The AKI risk score was relatively stable. Urine could be collected without dry ice or liquid nitrogen and kept for up to 8 weeks with either -20 or -80°C freezing with stable NephroCheck® results.en
dc.subjectAcute kidney injuryen
dc.subjectAcute kidney injury risk scoreen
dc.subjectCritical careen
dc.subjectInsulin-like growth factor binding protein-7en
dc.subjectTissue inhibitor of metalloproteinases-2en
dc.titleNephroCheck® Quality Test.en
dc.typeJournal Articleen
dc.identifier.journaltitleBlood purificationen
dc.identifier.affiliationDepartment of Intensive Care, Academic Medical Center, Amsterdam, The Netherlandsen
dc.identifier.affiliationAustralian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationCentre for Integrated Critical Care, The University of Melbourne, Melbourne, Victoria, Australiaen
dc.identifier.affiliationIntensive Careen
dc.identifier.affiliationDepartment of Intensive Care, Siriraj Hospital, Mahidol University, Bangkok, Thailand..en
dc.identifier.affiliationDepartment of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazilen
dc.identifier.affiliationData Analytics Research and Evaluation (DARE) Centreen
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