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https://ahro.austin.org.au/austinjspui/handle/1/22701
Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Naorungroj, Thummaporn | - |
dc.contributor.author | Neto, Ary Serpa | - |
dc.contributor.author | Fujii, Tomoko | - |
dc.contributor.author | Jude, Briony | - |
dc.contributor.author | Udy, Andrew | - |
dc.contributor.author | Bellomo, Rinaldo | - |
dc.date.accessioned | 2020-03-02T03:28:02Z | - |
dc.date.available | 2020-03-02T03:28:02Z | - |
dc.date.issued | 2020-03 | - |
dc.identifier.citation | Critical Care and Resuscitation 2020; 22(1): 83-85 | - |
dc.identifier.issn | 1441-2772 | - |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/22701 | - |
dc.description.abstract | The benefit of intravenous sodium bicarbonate administration in patients with severe metabolic acidosis remains controversial, partly due to lack of double-blind trials. From a practical viewpoint, such blinding requires testing of the stability of sodium bicarbonate in polyolefin bags. We examined seven samples of 100 mL 8.4% sodium bicarbonate diluted in 150 mL normal saline within a 250 mL polyolefin bag at time 0, 24 and 48 hours after preparation. We measured pH, Pco2, and bicarbonate concentration. Over a period of 48 hours, both pH and Pco2 decreased significantly (hourly rate of change, -0.001 [P = 0.043) and -0.098 [P < 0.001] respectively). However, the concentration of bicarbonate did not decrease, with an hourly rate of change of only -0.009 (P = 0.42). When 100 mL of 8.4% sodium bicarbonate are diluted in 150 mL of normal saline within a 250 mL polyolefin bag, changes in pH and Pco2 over a 48-hour period are small and bicarbonate concentration remains stable. | - |
dc.language.iso | eng | - |
dc.title | Stability of bicarbonate in normal saline: a technical report. | - |
dc.type | Journal Article | - |
dc.identifier.journaltitle | Critical Care and Resuscitation | - |
dc.identifier.affiliation | Department of Intensive Care and Hyperbaric Medicine, Alfred Hospital, Melbourne, Vic, Australia | en |
dc.identifier.affiliation | Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia | en |
dc.identifier.affiliation | Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic, Australia | en |
dc.identifier.orcid | 0000-0002-1650-8939 | - |
dc.identifier.pubmedid | 32102647 | - |
dc.type.austin | Journal Article | - |
local.name.researcher | Bellomo, Rinaldo | |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairetype | Journal Article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Intensive Care | - |
crisitem.author.dept | Intensive Care | - |
crisitem.author.dept | Data Analytics Research and Evaluation (DARE) Centre | - |
Appears in Collections: | Journal articles |
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