Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/22456
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dc.contributor.authorKutaiba, Numan-
dc.contributor.authorLukies, Matthew-
dc.contributor.authorGalea, Michael-
dc.contributor.authorBegbie, Mark-
dc.contributor.authorSmith, Gerard-
dc.contributor.authorKearney, Leighton G-
dc.contributor.authorSpelman, Tim-
dc.contributor.authorLim, Ruth P-
dc.date2019-12-24-
dc.date.accessioned2020-01-20T05:24:56Z-
dc.date.available2020-01-20T05:24:56Z-
dc.date.issued2020-04-
dc.identifier.citationClinical Imaging 2020; 60(2): 194-199en_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/22456-
dc.description.abstractThe purpose of our study was to compare coronary luminal diameters in patients undergoing coronary computed tomography angiography (CCTA) performed with different sublingual nitroglycerin (NTG) spray regimens. We retrospectively reviewed CCTA studies performed in two historical groups (Group 1, single dose nitroglycerin 2 min prior to CCTA, and Group 2, single dose 10 min prior), and a current protocol group (Group 3, single dose at 2 and 10 min prior). Thirty patients were evaluated per group. Two blinded readers measured coronary luminal diameters with comparison of diameter measurements. A third blinded reader assessed image quality of coronary artery segments. Significant group-level differences in median luminal diameters were identified. Higher median diameters (95% CI) across all segments of 0.40 mm (0.20, 0.60) for Group 2 versus 1 and 0.50 mm (0.30, 0.70) for Group 3 versus 1 were recorded (both P < 0.001). No significant differences in median luminal diameters were found between Groups 2 and 3. No significant differences in image quality were found among the groups apart from higher image quality for the distal LAD for both Groups 2 and 3 compared to Group 1. Sublingual nitroglycerin spray administered as a single dose at 10 minute dilates coronary arteries more than when only administered at 2 min prior to CCTA. Combined two doses at 10 and 2 min prior to CCTA do not yield further dilatation of coronary arteries.en_US
dc.language.isoeng-
dc.subjectAtherosclerosisen_US
dc.subjectComputed tomographyen_US
dc.subjectCoronary arterial sizeen_US
dc.subjectCoronary artery diseaseen_US
dc.subjectCoronary computed tomography angiographyen_US
dc.titleThe effects of sublingual nitroglycerin administration in coronary computed tomography angiography.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleClinical Imagingen_US
dc.identifier.affiliationRadiologyen_US
dc.identifier.affiliationKarolinska Institute, Stockholm, Sweden.en_US
dc.identifier.affiliationThe University of Melbourne, Parkville, VIC 3010, Australiaen_US
dc.identifier.affiliationBurnet Institute, 55 Commercial Road, Melbourne, VIC 3004, Australiaen_US
dc.identifier.affiliationCardiologyen_US
dc.identifier.doi10.1016/j.clinimag.2019.11.019en_US
dc.type.contentTexten_US
dc.identifier.orcid0000-0003-4627-9847en_US
dc.identifier.pubmedid31927493-
dc.type.austinJournal Article-
local.name.researcherGalea, Michael
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptRadiology-
crisitem.author.deptRadiology-
crisitem.author.deptCardiology-
crisitem.author.deptRadiology-
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