Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/22145
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dc.contributor.authorValentine, Jake C-
dc.contributor.authorMorrissey, C Orla-
dc.contributor.authorTacey, Mark A-
dc.contributor.authorLiew, Danny-
dc.contributor.authorPatil, Sushrut-
dc.contributor.authorAnanda-Rajah, Michelle-
dc.date2019-12-04-
dc.date.accessioned2019-12-04T01:53:27Z-
dc.date.available2019-12-04T01:53:27Z-
dc.date.issued2020-02-
dc.identifier.citationMycoses 2020; 63(2): 162-171en
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/22145-
dc.description.abstractInvasive fungal diseases (IFD) are associated with significant treatment related costs in patients with haematological malignancies (HM). The objectives of this study were to characterise the gross and attributable hospitalisation costs of a variety of IFD in patients with HM by linking state-wide hospital administrative and costing datasets. We linked the Victorian Admitted Episodes Dataset, Victorian Cancer Registry and the Victorian Cost Data Collection from 1st July 2009 to 30th June 2015. IFD-cases and uninfected controls were matched 1:1 based on age within ten-years, same underlying HM and length of stay prior to IFD diagnosis. The cost difference between surviving cases and controls, indexed to 2019 Australian dollars (AUD) calculated twelve-months from IFD diagnosis, was determined using Poisson and negative binomial regression (NBR). From 334 matched-pairs, the gross hospitalisation cost of cases was AUD$67,277 compared to AUD$51,158 among uninfected controls, associated with an excess median hospitalisation cost of AUD$16,119 (p<0.001) attributable to IFD, approximating to USD$11,362 and €10,154 at purchasing power parity. Median attributable costs were highest for patients with invasive aspergillosis (AUD$55,642; p<0.001) and mucormycosis (AUD$51,272; p=0.043) followed by invasive candidiasis AUD$24,572 (p<0.001). No change in median excess attributable costs was observed over the study period (p=0.90) Analyses by NBR revealed a 1.36-fold increase (p<0.001) in total hospitalisation costs among cases as compared to controls twelve-months from IFD diagnosis. Invasive aspergillosis and mucormycosis have high attributable hospitalisation costs but the overall excess IFD cost of AUD$16,119 is modest, potentially reflecting missed or miscoded fungal episodes arguing for better quality surveillance data at hospital level.en
dc.language.isoeng-
dc.subjectInvasive fungal diseaseen
dc.subjectdata linkageen
dc.subjecthealth economicsen
dc.subjecthospitalisation costsen
dc.subjectsurveillanceen
dc.titleA population-based analysis of attributable hospitalisation costs of invasive fungal diseases in haematological malignancy patients using data linkage of state-wide registry and costing databases: 2009 - 2015.en
dc.typeJournal Articleen
dc.identifier.journaltitleMycosesen
dc.identifier.affiliationDepartment of Infectious Diseases, Alfred Health and Central Clinical School, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationMalignant Haematology and Stem Cell Transplantation Service, Alfred Health, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationRadiation Oncologyen
dc.identifier.affiliationFaculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationMalignant Haematology and Stem Cell Transplantation Service, Alfred Health, Melbourne, Victoria, Australiaen
dc.identifier.affiliationGeneral Medicine Unit, Alfred Health, Melbourne, Victoria, Australiaen
dc.identifier.affiliationOlivia Newton-John Cancer Wellness and Research Centreen
dc.identifier.doi10.1111/myc.13033en
dc.type.contentTexten
dc.identifier.pubmedid31715052-
dc.type.austinJournal Article-
local.name.researcherTacey, Mark A
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
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