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dc.contributor.authorLjimani, Alexandra-
dc.contributor.authorCaroli, Anna-
dc.contributor.authorLaustsen, Christoffer-
dc.contributor.authorFrancis, Susan-
dc.contributor.authorMendichovszky, Iosif Alexandru-
dc.contributor.authorBane, Octavia-
dc.contributor.authorNery, Fabio-
dc.contributor.authorSharma, Kanishka-
dc.contributor.authorPohlmann, Andreas-
dc.contributor.authorDekkers, Ilona A-
dc.contributor.authorVallee, Jean-Paul-
dc.contributor.authorDerlin, Katja-
dc.contributor.authorNotohamiprodjo, Mike-
dc.contributor.authorLim, Ruth P-
dc.contributor.authorPalmucci, Stefano-
dc.contributor.authorSerai, Suraj D-
dc.contributor.authorPeriquito, Joao-
dc.contributor.authorWang, Zhen Jane-
dc.contributor.authorFroeling, Martijn-
dc.contributor.authorThoeny, Harriet C-
dc.contributor.authorPrasad, Pottumarthi-
dc.contributor.authorSchneider, Moritz-
dc.contributor.authorNiendorf, Thoralf-
dc.contributor.authorPullens, Pim-
dc.contributor.authorSourbron, Steven-
dc.contributor.authorSigmund, Eric E-
dc.identifier.citationMagma (New York, N.Y.) 2019; online first: 1 November-
dc.description.abstractStandardization is an important milestone in the validation of DWI-based parameters as imaging biomarkers for renal disease. Here, we propose technical recommendations on three variants of renal DWI, monoexponential DWI, IVIM and DTI, as well as associated MRI biomarkers (ADC, D, D*, f, FA and MD) to aid ongoing international efforts on methodological harmonization. Reported DWI biomarkers from 194 prior renal DWI studies were extracted and Pearson correlations between diffusion biomarkers and protocol parameters were computed. Based on the literature review, surveys were designed for the consensus building. Survey data were collected via Delphi consensus process on renal DWI preparation, acquisition, analysis, and reporting. Consensus was defined as ≥ 75% agreement. Correlations were observed between reported diffusion biomarkers and protocol parameters. Out of 87 survey questions, 57 achieved consensus resolution, while many of the remaining questions were resolved by preference (65-74% agreement). Summary of the literature and survey data as well as recommendations for the preparation, acquisition, processing and reporting of renal DWI were provided. The consensus-based technical recommendations for renal DWI aim to facilitate inter-site harmonization and increase clinical impact of the technique on a larger scale by setting a framework for acquisition protocols for future renal DWI studies. We anticipate an iterative process with continuous updating of the recommendations according to progress in the field.-
dc.titleConsensus-based technical recommendations for clinical translation of renal diffusion-weighted MRI.-
dc.typeJournal Article-
dc.identifier.journaltitleMagma (New York, N.Y.)-
dc.identifier.affiliationMR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark-
dc.identifier.affiliationSir Peter Mansfield Imaging Centre, University Park, University of Nottingham, Nottingham, NG7 2RD, UK-
dc.identifier.affiliationDepartment of Radiology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK-
dc.identifier.affiliationDevelopmental Imaging and Biophysics Section, UCL Great Ormond Street Institute of Child Health, London, UK-
dc.identifier.affiliationImaging Biomarkers Group, Department of Biomedical Imaging Sciences, University of Leeds, Leeds, UK-
dc.identifier.affiliationDepartment of Diagnostic, Geneva University Hospital and University of Geneva, 1211, Geneva-14, Switzerland-
dc.identifier.affiliationDepartment of Radiology, Hôpital Cantonal Fribourgois (HFR), University of Fribourg, 1708, Fribourg, Switzerland-
dc.identifier.affiliationImaging Biomarkers Group, Department of Biomedical Imaging Sciences, University of Leeds, Leeds, UK-
dc.identifier.affiliationDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, Moorenstr. 5, 40225, Düsseldorf, Germanyen
dc.identifier.affiliationDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USAen
dc.identifier.affiliationDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USAen
dc.identifier.affiliationTranslational and Molecular Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USAen
dc.identifier.affiliationDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlandsen
dc.identifier.affiliationBerlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, 13125, Berlin, Germanyen
dc.identifier.affiliationDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology I Unit, University Hospital "Policlinico-Vittorio Emanuele", University of Catania, Catania, Italyen
dc.identifier.affiliationDepartment of Radiology, Hannover Medical School, Hannover, Germanyen
dc.identifier.affiliationDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlandsen
dc.identifier.affiliationDepartment of Radiology, Center for Biomedical Imaging (CBI), Center for Advanced Imaging Innovation and Research (CAI2R), NYU Langone Health, New York, NY, USAen
dc.identifier.affiliationDepartment of Radiology, Center for Advanced Imaging, NorthShore University Health System, Evanston, IL, USAen
dc.identifier.affiliationComprehensive Pneumology Center, German Center for Lung Research, Munich, Germanyen
dc.identifier.affiliationDepartment of Radiology, University Hospital Tuebingen, Tübingen, Germanyen
dc.identifier.affiliationDepartment of Biomedical Engineering, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italyen
dc.identifier.affiliationDepartment of Radiology, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDie Radiologie, Munich, Germanyen
dc.identifier.affiliationGhent Institute for Functional and Metabolic Imaging, Ghent University, Ghent, Belgiumen
dc.identifier.affiliationDepartment of Radiology, University Hospital Ghent, Ghent, Belgiumen
dc.identifier.affiliationDepartment of Radiology, University Hospital, LMU Munich, Munich, Germanyen
dc.identifier.affiliationThe University of Melbourne, Melbourne, Victoria, Australia-
dc.type.austinJournal Article-
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