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dc.contributor.authorGaudino, Mario-
dc.contributor.authorBenedetto, Umberto-
dc.contributor.authorFremes, Stephen E-
dc.contributor.authorHare, David L-
dc.contributor.authorHayward, Philip-
dc.contributor.authorMoat, Neil-
dc.contributor.authorMoscarelli, Marco-
dc.contributor.authorDi Franco, Antonino-
dc.contributor.authorNasso, Giuseppe-
dc.contributor.authorPeric, Miodrag-
dc.contributor.authorPetrovic, Ivana-
dc.contributor.authorCollins, Peter-
dc.contributor.authorWebb, Carolyn M-
dc.contributor.authorPuskas, John D-
dc.contributor.authorSpeziale, Giuseppe-
dc.contributor.authorYoo, Kyung Jong-
dc.contributor.authorGirardi, Leonard N-
dc.contributor.authorTaggart, David P-
dc.identifier.citationThe Annals of Thoracic Surgery 2020; 109(3): 688-694en_US
dc.description.abstractWe used a large patient-level dataset including six angiographic randomized trials (RCTs) on coronary artery bypass conduits to explore incidence and determinants of coronary graft failure. Patient-level angiographic data of six RCTs comparing long-term outcomes of the radial artery and other conduits were joined. Primary outcome was graft occlusion at maximum follow-up. The analysis was divided as follows: 1) left anterior descending coronary (LAD) distribution, 2) non-LAD distribution (circumflex and right coronary artery). To identify predictors of graft occlusion, mixed model multivariable Cox regression including all baseline characteristics with stratification by individual trials was used. 1091 patients and 2281 grafts were included (921 left internal mammary arteries, 74 right internal mammary arteries, 710 radial artery and 576 saphenous veins; all left internal mammary arteries were used on the LAD, the other conduits were used on the non-LAD distribution; mean angiographic follow up: 65±29 months). Occlusion rate was 2.3%, 13.5%, 9.4%, 17.5% for the left internal mammary arteries, right internal mammary arteries, radial artery and saphenous veins, respectively. At multivariable analysis type of conduit used, age, female gender, left ventricular ejection fraction<50% and use of the Y graft were significantly associated with graft occlusion in the non-LAD distribution. Our analyses showed that failure of the left internal mammary arteries to LAD bypass is a very uncommon event. For the non-LAD distribution, the non-use of radial artery, age, female gender, left ventricular ejection fraction<50% and use of the Y graft configuration were significantly associated with mid-term graft failure.en_US
dc.subjectradial arteryen_US
dc.titleAngiographic outcome of coronary artery bypass grafts: Radial Artery Database International Alliance.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleThe Annals of Thoracic Surgeryen_US
dc.identifier.affiliationDepartment of Cardiothoracic Surgery, Cornell Medicine, New York, USen_US
dc.identifier.affiliationAustin Healthen_US
dc.identifier.affiliationUniversity of Melbourne, Melbourne, Australiaen_US
dc.identifier.affiliationBristol Heart Institute, Bristol, UKen_US
dc.identifier.affiliationSchulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canadaen_US
dc.identifier.affiliationRoyal Brompton & Harefield Trust, London, UKen_US
dc.identifier.affiliationAnthea Hospital, Bari, Italyen_US
dc.identifier.affiliationDepartment of Cardiothoracic Surgery, Cornell Medicine, New York, USen_US
dc.identifier.affiliationAnthea Hospital, Bari, Italyen_US
dc.identifier.affiliationDedinje Cardiovascular Institute and Belgrade University School of Medicine, Belgrade, Serbiaen_US
dc.identifier.affiliationNational Heart & Lung Institute, Imperial College London, London, UKen_US
dc.identifier.affiliationIcahn School of Medicine at Mount Sinai, New York City, USen_US
dc.identifier.affiliationYonsei University College of Medicine, Seoul, Koreaen_US
dc.identifier.affiliationDepartment of Cardiothoracic Surgery, Cornell Medicine, New York, USen_US
dc.identifier.affiliationUniversity of Oxford, Oxford, UKen_US
dc.type.austinJournal Article-, David L
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
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