Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/21504
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dc.contributor.authorChi, Lap Hing-
dc.contributor.authorBurrows, Allan D-
dc.contributor.authorAnderson, Robin L-
dc.date2019-04-
dc.date.accessioned2019-08-12T05:01:10Z-
dc.date.available2019-08-12T05:01:10Z-
dc.date.issued2019-07-05-
dc.identifier.citationGrowth factors 2019: 37(1-2): 12-28-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/21504-
dc.description.abstractBreast cancer is the most prevalent type of cancer amongst women worldwide. The mortality rate for patients with early-stage breast cancer has been decreasing, however, the 5-year survival rate for patients with metastatic disease remains poor, currently at 27%. Here, we have reviewed the current understanding of the role of bone morphogenetic protein (BMP) signaling in breast cancer progression, and have highlighted the discordant results that are reported in different studies. We propose that some of these contradictory outcomes may result from signaling through either the canonical or non-canonical pathways in different cell lines and tumors, or from different tumor-stromal interactions that occur in vivo.-
dc.language.isoeng-
dc.subjectBreast cancer-
dc.subjectSMAD4-
dc.subjectbone morphogenetic proteins-
dc.subjectsignaling-
dc.titleBone morphogenetic protein signaling in breast cancer progression.-
dc.typeJournal Article-
dc.identifier.journaltitleGrowth factors-
dc.identifier.affiliationMetastasis Research Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationSchool of Cancer Medicine, La Trobe University, Bundoora, Australiaen
dc.identifier.affiliationDepartment of Clinical Pathology, The University of Melbourne, Parkville, Victoria, Australiaen
dc.identifier.affiliationSir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Australiaen
dc.identifier.doi10.1080/08977194.2019.1626378-
dc.identifier.orcid0000-0003-0983-3474-
dc.identifier.orcid0000-0003-0595-1414-
dc.identifier.orcid0000-0002-6841-7422-
dc.identifier.pubmedid31272247-
dc.type.austinJournal Article-
local.name.researcherAnderson, Robin L
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptOlivia Newton-John Cancer Research Institute-
Appears in Collections:Journal articles
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