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https://ahro.austin.org.au/austinjspui/handle/1/21385| Title: | Genomics of vancomycin-resistant Enterococcus faecium. | Austin Authors: | Gorrie, Claire;Higgs, Charlie;Carter, Glen;Stinear, Timothy P;Howden, Benjamin P | Affiliation: | Microbiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia Doherty Applied Microbial Genomics, Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia |
Issue Date: | Jul-2019 | Date: | 2019-07-22 | Publication information: | Microbial genomics 2019; 5(7) | Abstract: | Vancomycin-resistant Enterococcus faecium (VREfm) is a globally significant public health threat and was listed on the World Health Organization's 2017 list of high-priority pathogens for which new treatments are urgently needed. Treatment options for invasive VREfm infections are very limited, and outcomes are often poor. Whole-genome sequencing is providing important new insights into VREfm evolution, drug resistance and hospital adaptation, and is increasingly being used to track VREfm transmission within hospitals to detect outbreaks and inform infection control practices. This mini-review provides an overview of recent data on the use of genomics to understand and respond to the global problem of VREfm. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/21385 | DOI: | 10.1099/mgen.0.000283 | ORCID: | 0000-0003-0237-1473 | Journal: | Microbial genomics | PubMed URL: | 31329096 | Type: | Journal Article | Subjects: | Enterococcus faecium antibiotic resistance whole-genome sequencing |
| Appears in Collections: | Journal articles |
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