Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/20296
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dc.contributor.authorOpdam, Helen I-
dc.date2019-01-24-
dc.date.accessioned2019-03-04T22:04:14Z-
dc.date.available2019-03-04T22:04:14Z-
dc.date.issued2019-04-
dc.identifier.citationCritical care clinics 2019; 35(2): 389-405-
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/20296-
dc.description.abstractOptimal supportive treatment of brain dead potential organ donors maximizes donation and transplant outcomes. Brain death is associated with activation of inflammatory pathways and loss of autoregulatory brain functions that may include hypothalamic-pituitary dysfunction. As well as general supportive care, specific treatment to counter the common sequelae of brain death such as hypotension, hypothermia, and diabetes insipidus is required. In addition, the provision of specific hormonal therapy (thyroid hormone, vasopressin, and steroids) has been proposed but is controversial due to lack of high level evidence to support its efficacy.-
dc.language.isoeng-
dc.subjectBrain death-
dc.subjectDonor management-
dc.subjectHormone therapy-
dc.subjectOrgan donation-
dc.subjectSteroids-
dc.subjectThyroid hormone-
dc.subjectTransplantation-
dc.subjectVasopressin-
dc.titleHormonal Therapy in Organ Donors.-
dc.typeJournal Article-
dc.identifier.journaltitleCritical care clinics-
dc.identifier.affiliationDepartment of Intensive Care, Austin Health, Heidelberg, Victoria, Australia-
dc.identifier.doi10.1016/j.ccc.2018.11.013-
dc.identifier.pubmedid30784617-
dc.type.austinJournal Article-
dc.type.austinReview-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.cerifentitytypePublications-
crisitem.author.deptIntensive Care-
Appears in Collections:Journal articles
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