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dc.contributor.authorKutaiba, Numan-
dc.contributor.authorArdalan, Zaid S M-
dc.contributor.authorPatwala, Kurvi-
dc.contributor.authorLau, Eddie-
dc.contributor.authorGoodwin, Mark D-
dc.contributor.authorGow, Paul J-
dc.identifier.citationTransplantation Direct 2018; 4(12): e408en_US
dc.description.abstractThe purpose of this study was to review the value of bone scans (BS) in the assessment of bone metastases from early-stage hepatocellular carcinoma (HCC) in patients assessed or waiting for liver transplant (LTx). We reviewed BS studies performed at our center for patients with early-stage HCC either being assessed for LTx, or on the waiting list for LTx, from January 2010 to May 2017. The BS findings were classified as positive, equivocal, or negative. Correlation with final outcome based on clinical and radiological follow-up was performed. There were 360 BS performed in 186 patients during the study period with a mean age of 58.7 years (range, 34.9-70.4 years) and most were male patients (161/186 [86.6%]). None of the BSs resulted in delisting of patients from the LTx waiting list. Three BSs were reported as positive for metastases. All 3 were proven to be false positives on follow-up. Fourteen studies reported equivocal findings, none of which were confirmed to be metastases on follow-up. There was 1 false-negative BS: a bone metastasis was detected incidentally on magnetic resonance imaging and proven on biopsy. We have demonstrated that the diagnostic yield of BS in early HCC patients who are candidates for LTx is minimal, challenging the current inclusion of BS in guidelines for staging these HCC patients.en_US
dc.titleValue of Bone Scans in Work-up of Patients With Hepatocellular Carcinoma for Liver Transplant.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleTransplantation Directen_US
dc.identifier.affiliationThe University of Melbourne, Victoria, Australiaen_US
dc.identifier.affiliationMolecular Imaging and Therapyen_US
dc.identifier.affiliationVictorian Liver Transplant Uniten_US
dc.type.austinJournal Article-, Mark D
item.openairetypeJournal Article-
item.fulltextNo Fulltext- Liver Transplant Unit- and Hepatology-
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