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dc.contributor.authorPhan, Kevin-
dc.contributor.authorMaingard, Julian-
dc.contributor.authorKok, Hong Kuan-
dc.contributor.authorDmytriw, Adam A-
dc.contributor.authorGoyal, Sourabh-
dc.contributor.authorChandra, Ronil-
dc.contributor.authorBrooks, Duncan Mark-
dc.contributor.authorThijs, Vincent N-
dc.contributor.authorAsadi, Hamed-
dc.identifier.citationNeurointervention 2018; 13(2): 100-109-
dc.description.abstractThe evidence for endovascular therapy and choice of technique in distal middle cerebral artery (MCA) M2 segment occlusions in acute ischemic stroke remains controversial. We aimed to conduct a systematic review and meta-analysis primarily comparing reperfusion rates of stent-retrieval versus contact aspiration for M2 occlusions. Study selection included cohorts of patients with distal MCA occlusions in acute ischemic strokes treated with an endovascular approach including stent-retrieval or contact aspiration. Twelve studies were selected for meta-analysis for a total of 835 cases. Meta-analysis by proportions was conducted on parameters including baseline and procedural characteristics, thrombolysis in cerebral infarction (TICI) 2b-3 outcomes, and 90-day modified Rankin scale (mRS) outcomes. Hypertension and hyperlipidemia were more prevalent in stent-retriever patients. Pooled baseline National Institute of Health Stroke Scale scores and Alberta Stroke Program Early Computed Tomography Score imaging scores were similar. Pooled time onset of symptoms to door arrival was higher for the stent-retrieval group (154 vs. 97.4 minutes, P=0.01), as was time to groin puncture (259.9 vs. 156.2 minutes, P=0.02), but there was no difference in procedure time. The TICI 2b-3 recanalization rate was similar (80.5% vs. 86.8%, P=0.168). The frequency of mRS 0-2 at 90-day was also similar (74.5% vs. 59.9%, P=0.120), and an excellent mRS 0-1 was lower for stent-retrievers (39.9% vs. 65.6%, P=0.003). A significant negative correlation was found between onset to groin puncture time and the proportion of patients with a good mRS (r=-0.71, P=0.048). Both endovascular techniques achieved recanalization rates greater than 80% and 90-day outcomes of minimal disability with similar complication rates. The literature is skewed by aspiration cases being performed sooner after onset of stroke compared to stent-retriever cases.-
dc.subjectCerebrovascular disorders-
dc.subjectEndovascular procedures-
dc.subjectMiddle cerebral artery-
dc.titleContact Aspiration versus Stent-Retriever Thrombectomy for Distal Middle Cerebral Artery Occlusions in Acute Ischemic Stroke: Meta-Analysis.-
dc.typeJournal Article-
dc.identifier.affiliationDepartment of Neurology, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationInterventional Neuroradiology Unit, Monash Imaging, Monash Health, Clayton, Australiaen
dc.identifier.affiliationStroke Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australiaen
dc.identifier.affiliationNeuroSpine Surgery Research Group, Prince of Wales Private Hospital, Randwick, Australiaen
dc.identifier.affiliationDepartment of Neurosurgery, Prince of Wales Hospital, Randwick, Australiaen
dc.identifier.affiliationInterventional Neuroradiology Service, Department of Radiology, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Radiology, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Australiaen
dc.identifier.affiliationDepartment of Interventional Radiology, Guy's and St Thomas' NHS Foundation Trust, London, UKen
dc.identifier.affiliationDepartment of Radiology, University of Toronto, Toronto, Canadaen
dc.type.austinJournal Article-, Hamed
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.openairecristype Florey Institute of Neuroscience and Mental Health-
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