Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/19598
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Khoo, Kaylyn | - |
dc.contributor.author | Lew, Jeremy F | - |
dc.contributor.author | Neef, Pieter A | - |
dc.contributor.author | Kearney, Leighton G | - |
dc.contributor.author | Churilov, Leonid | - |
dc.contributor.author | Robbins, Raymond J | - |
dc.contributor.author | Tan, Alanna | - |
dc.contributor.author | Hachem, M | - |
dc.contributor.author | Owen-Jones, L | - |
dc.contributor.author | Lam, Que T | - |
dc.contributor.author | Hart, Alanna | - |
dc.contributor.author | Wilson, A | - |
dc.contributor.author | Sumithran, Priya | - |
dc.contributor.author | Johnson, Douglas F | - |
dc.contributor.author | Srivastava, Piyush M | - |
dc.contributor.author | Farouque, Omar | - |
dc.contributor.author | Burrell, Louise M | - |
dc.contributor.author | Zajac, Jeffrey D | - |
dc.contributor.author | Ekinci, Elif I | - |
dc.date | 2018-09-10 | - |
dc.date.accessioned | 2018-10-11T02:51:45Z | - |
dc.date.available | 2018-10-11T02:51:45Z | - |
dc.date.issued | 2018-09-10 | - |
dc.identifier.citation | Scientific Reports 2018; 8(1): 13564 | en_US |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/19598 | - |
dc.description.abstract | Diabetes is an independent risk factor for development of heart failure and has been associated with poor outcomes in these patients. The prevalence of diabetes continues to rise. Using routine HbA1c measurements on inpatients at a tertiary hospital, we aimed to investigate the prevalence of diabetes amongst patients hospitalised with decompensated heart failure and the association of dysglycaemia with hospital outcomes and mortality. 1191 heart failure admissions were identified and of these, 49% had diabetes (HbA1c ≥ 6.5%) and 34% had pre-diabetes (HbA1c 5.7-6.4%). Using a multivariable analysis adjusting for age, Charlson comorbidity score (excluding diabetes and age) and estimated glomerular filtration rate, diabetes was not associated with length of stay (LOS), Intensive Care Unit (ICU) admission or 28-day readmission. However, diabetes was associated with a lower risk of 6-month mortality. This finding was also supported using HbA1c as a continuous variable. The diabetes group were more likely to have diastolic dysfunction and to be on evidence-based cardiac medications. These observational data are hypothesis generating and possible explanations include that more diabetic patients were on medications that have proven mortality benefit or prevent cardiac remodelling, such as renin-angiotensin system antagonists, which may modulate the severity of heart failure and its consequences. | en_US |
dc.language.iso | eng | - |
dc.title | Routine use of HbA1c amongst inpatients hospitalised with decompensated heart failure and the association of dysglycaemia with outcomes. | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journaltitle | Scientific Reports | en_US |
dc.identifier.affiliation | Endocrinology | en_US |
dc.identifier.affiliation | Medicine (University of Melbourne) | en_US |
dc.identifier.affiliation | Cardiology | en_US |
dc.identifier.affiliation | The Florey Institute of Neuroscience and Mental Health | en_US |
dc.identifier.affiliation | Strategy, Quality & Service Redesign, Austin Health, Heidelberg, Victoria, Australia | en_US |
dc.identifier.affiliation | Austin Centre for Applied Clinical Informatics, Austin Health, Heidelberg, Victoria, Australia | en_US |
dc.identifier.affiliation | Pathology | en_US |
dc.identifier.affiliation | Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia | en_US |
dc.identifier.affiliation | Health and Biomedical Informatics Centre, University of Melbourne, Parkville, 3010, Victoria, Australia | en_US |
dc.identifier.affiliation | St Vincent's Hospital Melbourne, Fitzroy, 3065, Victoria, Australia | en_US |
dc.identifier.affiliation | General Medicine | en_US |
dc.identifier.doi | 10.1038/s41598-018-31473-8 | en_US |
dc.type.content | Text | en_US |
dc.identifier.orcid | 0000-0002-9807-6606 | en_US |
dc.identifier.orcid | 0000-0003-1863-7539 | en_US |
dc.identifier.orcid | 0000-0002-7143-7387 | en_US |
dc.identifier.orcid | 0000-0003-2372-395X | en_US |
dc.identifier.pubmedid | 30202020 | - |
dc.type.austin | Journal Article | - |
local.name.researcher | Burrell, Louise M | |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.openairetype | Journal Article | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Medicine (University of Melbourne) | - |
crisitem.author.dept | General Medicine | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Medicine (University of Melbourne) | - |
crisitem.author.dept | The Florey Institute of Neuroscience and Mental Health | - |
crisitem.author.dept | Clinical Analytics and Reporting | - |
crisitem.author.dept | Endocrinology | - |
crisitem.author.dept | Pathology | - |
crisitem.author.dept | Infectious Diseases | - |
crisitem.author.dept | Endocrinology | - |
crisitem.author.dept | Medicine (University of Melbourne) | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | General Medicine | - |
crisitem.author.dept | Medicine (University of Melbourne) | - |
crisitem.author.dept | Endocrinology | - |
crisitem.author.dept | Medicine (University of Melbourne) | - |
crisitem.author.dept | Endocrinology | - |
Appears in Collections: | Journal articles |
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