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Title: Venous leg ulcer healing with electric stimulation therapy: a pilot randomised controlled trial.
Austin Authors: Miller, C;McGuiness, W;Wilson, S;Cooper, K;Swanson, T;Rooney, D;Piller, N;Woodward, Michael M 
Affiliation: La Trobe University/Alfred Health, School of Nursing & Midwifery, La Trobe University, Australia
La Trobe University, School of Nursing & Midwifery, La Trobe University, Australia
La Trobe University/Austin Health, School of Nursing & Midwifery, La Trobe University, Australia
Nurse Practitioner Wound Management, South West Healthcare, Warrnambool. Vic 3280, Australia
Goulburn Valley Health, Home Nursing Services, Australia
Flinders University, Lymphoedema Clinical Research Unit, Department of Surgery, School of Medicine, Australia
Department of Continuing Care, Austin Health, Heidelberg, Victoria, Australia
Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Issue Date: 2-Mar-2017
Publication information: Journal of wound care 2017; 26(3): 88-98
Abstract: Compression therapy is a gold standard treatment to promote venous leg ulcer (VLU) healing. Concordance with compression therapy is, however, often sub-optimal. The aim of this study was to evaluate the effectiveness of electric stimulation therapy (EST) to facilitate healing of VLUs among people who do not use moderate-to-high levels of compression (>25 mmHg). A pilot multicentre, single-blinded randomised controlled trial was conducted. Participants were randomised (2:1) to the intervention group or a control group where EST or a sham device was used 4 times daily for 20 minutes per session. Participants were monitored fortnightly for eight weeks. The primary outcome measure was percentage of area (wound size) change. In the 23 patients recruited, an average redution in wound size of 23.15% (standard deviation [SD]: 61.23) was observed for the control group compared with 32.67 % (SD: 42.54) for the intervention. A moderate effect size favouring the intervention group was detected from univariate [F(1,18)=1.588, p=0.224, partial eta squared=0.081] and multivariate repeated measures [F(1,18)=2.053, p=0.169, partial eta squared=0.102] analyses. The pilot study was not powered to detect statistical significance, however, the difference in healing outcomes are encouraging. EST may be an effective adjunct treatment among patients who have experienced difficulty adhering to moderate-to-high levels of compression therapy.
DOI: 10.12968/jowc.2017.26.3.88
Journal: Journal of wound care
PubMed URL: 28277996
ISSN: 0969-0700
Type: Journal Article
Subjects: compression therapy
electric stimulation therapy
venous leg ulcer
wound healing
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