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Title: Advances in Neuroimaging for Neurodegenerative Disease.
Austin Authors: Veldsman, Michele;Egorova, Natalia
Affiliation: The Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria, Australia
Nuffield Department of Clinical Neuroscience, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Oxford, OX3 9DU, UK
Issue Date: 2017
Publisher: Springer, Cham
Publication information: Advances in neurobiology 2017; 15: 451-478
Series/Report no.: Advances in Neurobiology volume 15
Abstract: This chapter is intended as a primer to the most widely used neuroimaging methods available in the prediction, diagnosis and monitoring of the neurodegenerative diseases. We describe the imaging methods that allow us to examine brain structure, function and pathology and investigate neurodegenerative mechanisms in vivo. We describe methods to interrogate brain structure with magnetic resonance imaging (MRI), and brain function with molecular imaging, functional MRI and electro- and magneto-encephalography. We highlight the major neuroimaging advances, including brain stimulation and connectomics, which have brought new insights into a wide range of neurodegenerative diseases and describe some of the challenges in imaging clinical populations. Finally, we discuss the future of neuroimaging in neurodegenerative disease and its potential for generating predictive, diagnostic and prognostic biomarkers.
DOI: 10.1007/978-3-319-57193-5_18
Journal: Advances in neurobiology
PubMed URL: 28674993
ISSN: 2190-5215
Type: Journal Article
Subjects: Connectomics
Magnetic resonance imaging
Molecular imaging
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