Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMoore, Elizabeth-
dc.contributor.authorTobin, Antony-
dc.contributor.authorReid, David-
dc.contributor.authorSantamaria, John-
dc.contributor.authorPaul, Eldho-
dc.contributor.authorBellomo, Rinaldo-
dc.identifier.citationJournal of Cardiothoracic and Vascular Anesthesia 2015; 29(5): 1229-35-
dc.description.abstractTo assess whether or not a positive fluid balance masks acute kidney injury (AKI) and is associated with adverse outcomes after cardiac surgery. Retrospective analysis. Tertiary university-affiliated metropolitan hospital: single center. Three thousand two hundred seven consecutive cardiac surgical patients admitted to the ICU from July 1, 2004 to June 30, 2012. None. The authors used AKI Network criteria to classify AKI. They then adjusted creatinine levels for weight-corrected fluid balance and categorized patients into 3 groups: group A (No AKI); group B (AKI only after adjustment); group C (AKI before and after adjustment). No patients had "AKI" before but "No AKI" after adjustment. Among 2,171 patients with weight and baseline creatinine available, after adjusting for fluid balance, the proportion of patients classified with AKI increased from 25.3% to 37.2% (p<0.001). In patients with AKI only after adjustment (group B), ICU mortality approximated that of group C (1.9% v 3.1%, p = 0.35) but was almost 3 times greater than group A (1.9% v 0.7%, p = 0.04). For group B, use of renal replacement therapy also was greater than group A (4.3% v 1.5%, p = 0.004) but less than group C (4.3% v 14.4%, p<0.001). The same trend was found for ICU length of stay (p≤0.001) and other adverse outcomes. Patients with AKI diagnosed after correction for the effect of a positive fluid balance on serum creatinine concentration have more adverse outcomes than patients without AKI by conventional criteria, but fewer than patients with AKI by conventional criteria.-
dc.subjectacute kidney injury-
dc.subjectcardiac surgery-
dc.subjectcardiothoracic surgery-
dc.subjectfluid accumulation-
dc.subjectfluid balance-
dc.titleThe Impact of Fluid Balance on the Detection, Classification and Outcome of Acute Kidney Injury After Cardiac Surgery.-
dc.typeJournal Article-
dc.identifier.journaltitleJournal of Cardiothoracic and Vascular Anesthesia-
dc.identifier.affiliationSt. Vincent's Hospital..-
dc.identifier.affiliationANZIC Research Centre, School of Population Health and Preventive Medicine, Monash University-
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australia-
dc.type.austinJournal Article-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.cerifentitytypePublications- Care- Analytics Research and Evaluation (DARE) Centre-
Appears in Collections:Journal articles
Show simple item record

Page view(s)

checked on Feb 6, 2023

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.