Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMilley, Kristi M-
dc.contributor.authorNimmo, Judith S-
dc.contributor.authorBacci, Barbara-
dc.contributor.authorRyan, Stewart D-
dc.contributor.authorRichardson, Samantha J-
dc.contributor.authorDanks, Janine A-
dc.identifier.citationBiopreservation and biobanking 2015; 13(4): 247-54-
dc.description.abstractCanine tumors are valuable comparative oncology models. This research was designed to create a sustainable biobank of canine mammary tumors for breast cancer research. The aim was to provide a well-characterized sample cohort for specimen sharing, data mining, and long-term research aims. Canine mammary tumors are most frequently managed at a local veterinary clinic or hospital. We adopted a biobank framework based on a large number of participating veterinary hospitals and clinics acting as collection centers that were serviced by a centralized storage facility. Recruitment was targeted at rural veterinary clinics. A tailored, stable collection kit (DogMATIC) was designed that was used by veterinarians in remote or rural locations to collect both fresh and fixed tissue for submission to the biobank. To validate this methodology the kit design, collection rate, and sample quality were analyzed. The Australian Veterinary Cancer Biobank was established as a network of 47 veterinary clinics and three veterinary pathology laboratories spanning over 200,000 km(2). In the first 12 months, 30 canine mammary tumor cases were submitted via the DogMATIC kit. Pure intact RNA was isolated in over 80% of samples with an average yield of 14.49 μg. A large network biobank, utilizing off-site collection with the DogMATIC kit, was successfully coordinated. The creation of the Australian Veterinary Cancer Biobank has established a long-term, sustainable, comparative oncology research resource in Australia. There are broader implications for biobanking with this very different form of collection and banking.-
dc.titleDogMATIC--A Remote Biospecimen Collection Kit for Biobanking.-
dc.typeJournal Article-
dc.identifier.journaltitleBiopreservation and biobanking-
dc.identifier.affiliationDepartment of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationAustralian Specialized Animal Pathology Laboratories , Mulgrave, Australiaen
dc.identifier.affiliationFaculty of Veterinary Science, The University of Melbourne , Werribee, Australiaen
dc.identifier.affiliationSchool of Medical Sciences, RMIT University , Bundoora, Australiaen
dc.identifier.affiliationAustralian Veterinary Cancer Biobank , Bundoora, Australiaen
dc.type.austinJournal Article-
dc.type.austinMulticenter Study-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
Appears in Collections:Journal articles
Show simple item record

Page view(s)

checked on Jan 30, 2023

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.