Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/17877
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dc.contributor.authorLandoni, Giovanni-
dc.contributor.authorPisano, Antonio-
dc.contributor.authorLomivorotov, Vladimir-
dc.contributor.authorAlvaro, Gabriele-
dc.contributor.authorHajjar, Ludhmila-
dc.contributor.authorPaternoster, Gianluca-
dc.contributor.authorNigro Neto, Caetano-
dc.contributor.authorLatronico, Nicola-
dc.contributor.authorFominskiy, Evgeny-
dc.contributor.authorPasin, Laura-
dc.contributor.authorFinco, Gabriele-
dc.contributor.authorLobreglio, Rosetta-
dc.contributor.authorAzzolini, Maria Luisa-
dc.contributor.authorBuscaglia, Giuseppe-
dc.contributor.authorCastella, Alberto-
dc.contributor.authorComis, Marco-
dc.contributor.authorConte, Adele-
dc.contributor.authorConte, Massimiliano-
dc.contributor.authorCorradi, Francesco-
dc.contributor.authorDal Checco, Erika-
dc.contributor.authorDe Vuono, Giovanni-
dc.contributor.authorGanzaroli, Marco-
dc.contributor.authorGarofalo, Eugenio-
dc.contributor.authorGazivoda, Gordana-
dc.contributor.authorLembo, Rosalba-
dc.contributor.authorMarianello, Daniele-
dc.contributor.authorBaiardo Redaelli, Martina-
dc.contributor.authorMonaco, Fabrizio-
dc.contributor.authorTarzia, Valentina-
dc.contributor.authorMucchetti, Marta-
dc.contributor.authorBelletti, Alessandro-
dc.contributor.authorMura, Paolo-
dc.contributor.authorMusu, Mario-
dc.contributor.authorPala, Giovanni-
dc.contributor.authorPaltenghi, Massimiliano-
dc.contributor.authorPasyuga, Vadim-
dc.contributor.authorPiras, Desiderio-
dc.contributor.authorRiefolo, Claudio-
dc.contributor.authorRoasio, Agostino-
dc.contributor.authorRuggeri, Laura-
dc.contributor.authorSantini, Francesco-
dc.contributor.authorSzékely, Andrea-
dc.contributor.authorVerniero, Luigi-
dc.contributor.authorVezzani, Antonella-
dc.contributor.authorZangrillo, Alberto-
dc.contributor.authorBellomo, Rinaldo-
dc.date2016-08-02-
dc.date.accessioned2018-06-19T06:23:59Z-
dc.date.available2018-06-19T06:23:59Z-
dc.date.issued2017-04-
dc.identifier.citationJournal of Cardiothoracic and Vascular Anesthesia 2017; 31(2): 719-730-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/17877-
dc.description.abstractOf the 230 million patients undergoing major surgical procedures every year, more than 1 million will die within 30 days. Thus, any nonsurgical interventions that help reduce perioperative mortality might save thousands of lives. The authors have updated a previous consensus process to identify all the nonsurgical interventions, supported by randomized evidence, that may help reduce perioperative mortality. A web-based international consensus conference. The study comprised 500 clinicians from 61 countries. A systematic literature search was performed to identify published literature about nonsurgical interventions, supported by randomized evidence, showing a statistically significant impact on mortality. A consensus conference of experts discussed eligible papers. The interventions identified by the conference then were submitted to colleagues worldwide through a web-based survey. The authors identified 11 interventions contributing to increased survival (perioperative hemodynamic optimization, neuraxial anesthesia, noninvasive ventilation, tranexamic acid, selective decontamination of the gastrointestinal tract, insulin for tight glycemic control, preoperative intra-aortic balloon pump, leuko-depleted red blood cells transfusion, levosimendan, volatile agents, and remote ischemic preconditioning) and 2 interventions showing increased mortality (beta-blocker therapy and aprotinin). Interventions then were voted on by participating clinicians. Percentages of agreement among clinicians in different countries differed significantly for 6 interventions, and a variable gap between evidence and clinical practice was noted. The authors identified 13 nonsurgical interventions that may decrease or increase perioperative mortality, with variable agreement by clinicians. Such interventions may be optimal candidates for investigation in high-quality trials and discussion in international guidelines to reduce perioperative mortality.-
dc.language.isoeng-
dc.subjectanesthesia-
dc.subjectconsensus-
dc.subjectintensive care-
dc.subjectmortality-
dc.subjectperioperative care-
dc.titleRandomized Evidence for Reduction of Perioperative Mortality: An Updated Consensus Process.-
dc.typeJournal Article-
dc.identifier.journaltitleJournal of Cardiothoracic and Vascular Anesthesia-
dc.identifier.affiliationDepartment of Cardiac Anaesthesia and Intensive Care, IRCCS University Hospital San Martino IST, Genova, Italyen
dc.identifier.affiliationDivision of Cardiac Anaesthesia and Intensive Care, Azienda Ospedaliera Dei Colli, Monaldi Hospital, Naples, Italy-
dc.identifier.affiliationDepartment of Anaesthesia and Intensive Care, Academician EN Meshalkin Novosibirsk State Budget Research Institute of Circulation Pathology, Novosibirsk, Russia-
dc.identifier.affiliationDepartment of Anaesthesia and Intensive Care, Azienda Ospedaliera Universitaria "Mater Domini," Catanzaro, Italy-
dc.identifier.affiliationDisciplina de Anestesia, Incor-Hospital das Clinicas, Sao Paulo, Brazil-
dc.identifier.affiliationDepartment of Cardiovascular Anaesthesia and Intensive Care, Ospedale San Carlo, Potenza, Italy-
dc.identifier.affiliationDante Pazzanese Institute of Cardiology, Department of Anesthesia and Intensive Care, Sao Paulo, Brazil-
dc.identifier.affiliationDepartment of Anaesthesia and Intensive Care, Spedali Civili, Brescia, Italy-
dc.identifier.affiliationDepartment of Cardiac Anaesthesia and Intensive Care, San Giovanni Battista Hospital, University of Turin, Turin, Italy-
dc.identifier.affiliationDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy-
dc.identifier.affiliationCardiac and Vascular Department, Ospedale Mauriziano Umberto I, Torino, Italy-
dc.identifier.affiliationDepartment of Anesthesia and Intensive Care, Mater Dei Hospital, Bari, Italy-
dc.identifier.affiliationDepartment of Anaesthesia and Intensive Care, Ente Ospedaliero Ospedali Galliera, Genova, Italy-
dc.identifier.affiliationDepartment of Cardiothoracic and Vascular Anaesthesia and Intensive Care, Università degli Studi di Bologna-Azienda Ospedaliera Sant'Orsola-Malpighi, Bologna, Italy-
dc.identifier.affiliationDepartment of Anaesthesia and Intensive Care, Institute of Cardiovascular Diseases Dedinje, Belgrade, Serbia-
dc.identifier.affiliationDepartment of Thoracic and Cardiac Surgery, University of Siena, Siena, Italy-
dc.identifier.affiliationAnesthesia and Intensive Care Unit, Policlinico "Duilio Casula" AOU Cagliari, Department of Medical Sciences "M. Aresu," Cagliari, Italy-
dc.identifier.affiliationDepartment of Cardioanesthesia and Intensive Care, Ospedale Civile Santissima Annunziata, Sassari, Italy-
dc.identifier.affiliationCardiac Anaesthesia and Intensive Care, Federal Centre for Cardiac Surgery, Astrakhan, Russia-
dc.identifier.affiliationDepartment of Anaesthesia and Intensive Care, Ospedale Cardinal Massaia di Asti, Asti, Italy-
dc.identifier.affiliationDivision of Cardiac Surgery, IRCCS University Hospital San Martino IST, Genova, Ita-
dc.identifier.affiliationDepartment of Anaesthesiology and Intensive Care, Semmelweis Egyetem, Budapest, Hungary-
dc.identifier.affiliationDipartimento Cardio-Nefro-Polmonare, Sezione Terapia Intensiva Cardiochirurgica, Azienda Ospedaliero Universitaria di Parma, Parma, Italy-
dc.identifier.affiliationDepartment of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy-
dc.identifier.affiliationIntensive Care Unit, Austin Health, Heidelberg, Victoria, Australia-
dc.identifier.doi10.1053/j.jvca.2016.07.017-
dc.identifier.orcid0000-0002-1650-8939-
dc.identifier.pubmedid27693206-
dc.type.austinJournal Article-
dc.type.austinReview-
local.name.researcherBellomo, Rinaldo
item.languageiso639-1en-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptIntensive Care-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
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